Clamping of the aortic arch vessels during normothermic regional perfusion after circulatory death prevents the return of brain activity in a porcine model

FF Dalsgaard, N Moeslund, ZL Zhang… - …, 2022 - journals.lww.com
Background. The cerebral effect of clamping following normothermic regional perfusion (NRP)
in donation after circulatory death (DCD) remains unknown. We investigated the effect of …

[HTML][HTML] Ex-situ oxygenated hypothermic machine perfusion in donation after circulatory death heart transplantation following either direct procurement or in-situ …

N Moeslund, IA Ertugrul, MA Hu, FF Dalsgaard… - The Journal of Heart and …, 2023 - Elsevier
Background Heart transplantation in donation after circulatory death (DCD) relies on warm
perfusion using either in situ normothermic regional perfusion (NRP) or ex situ normothermic …

[HTML][HTML] Effects of ketone body 3-hydroxybutyrate on cardiac and mitochondrial function during donation after circulatory death heart transplantation

…, HE Bøtker, O Caspi, H Eiskjær, N Moeslund - Scientific Reports, 2024 - nature.com
… Infusion of 3-OHB (n = 5) or Ringer’s acetate (n = 9) was initiated at the onset of NRP and
until procurement in donors and reinitiated following implantation in recipient pigs with …

[HTML][HTML] Relevance of the Viborg Population Based Screening Programme (VISP) for Cardiovascular Conditions Among 67 Year Olds: Attendance Rate, Prevalence …

…, J Refsgaard, D Svenstrup, NJ Moeslund… - European Journal of …, 2023 - Elsevier
Objective To report sex specific overall attendance rate, prevalence of screen detected
cardiovascular conditions, proportion of unknown conditions before screening, and proportion …

Protocol for a cohort study to evaluate the effectiveness and cost-effectiveness of general population screening for cardiovascular disease: the Viborg Screening …

…, R Søgaard, J Refsgaard, D Svenstrup, NJ Moeslund… - BMJ open, 2023 - bmjopen.bmj.com
… JSL, RS, MD and AH were drafting the article and JR, DS, MB and N-JM contributed with
fruitful criticism during the preparation of the manuscript, and all have approved the final …

[HTML][HTML] Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy …

OK Hørsdal, N Moeslund, K Berg-Hansen… - Journal of Translational …, 2024 - Springer
… Eight 60-kg female Danish Landrace pigs were randomised into two groups (n = 4 per
group) using computer-generated randomisation. Randomisation was performed after …

Impact of sternotomy and pericardiotomy on cardiopulmonary haemodynamics in a large animal model

ME Kirk, VT Merit, N Moeslund… - Experimental …, 2023 - Wiley Online Library
… The sample size of the original study was calculated a priori as n = 6. We performed four
pilot studies, and the present secondary study was initiated on all 10 pigs to increase power. …

[HTML][HTML] Goal-directed fluid therapy does not improve early glomerular filtration rate in a porcine renal transplantation model

JK Eriksen, LH Nielsen, N Moeslund… - Anesthesia & …, 2020 - journals.lww.com
… E, HO-1 levels in HVFT (n = 14) an IGDT groups (n = 14). F, GSH levels in cortex as percentage
change in HVFT (n = 11) and IGDT groups (n = 11). mRNA levels were normalized to β-…

High oxygenation during normothermic regional perfusion after circulatory death is beneficial on donor cardiac function in a porcine model

N Moeslund, ZL Zhang, LB Ilkjaer, P Ryhammer… - …, 2022 - journals.lww.com
Background. Thoracoabdominal normothermic regional perfusion (NRP) is a new method
for in situ reperfusion and reanimation of potential donor organs in donation after circulatory …

Establishing an economical and widely accessible donation after circulatory death animal abattoir model for lung research using ex vivo lung perfusion

ZL Zhang, N Moeslund, MA Hu, R Hoffmann… - Artificial …, 2022 - Wiley Online Library
… Zhang Long Zhang and Niels Moeslund contributed equally to this work. … Running experiment,
data collection, critical revision of article, approval of article: Niels Moeslund and Michiel …