User profiles for Nirmal S Sharma

nirmal shyam sharma

Assistant Professor, Harvard Medical School, Brigham and Women's Hospital
Verified email at bwh.harvard.edu
Cited by 917

Modern use of extracorporeal life support in pregnancy and postpartum

NS Sharma, KM Wille, SC Bellot, E Diaz-Guzman - Asaio Journal, 2015 - journals.lww.com
Extracorporeal membrane oxygenation (ECMO) use during pregnancy and the postpartum
period are thought to be associated with an increased risk for maternal or fetal bleeding …

[HTML][HTML] Unique lipid signatures of extracellular vesicles from the airways of asthmatics

…, Y Wang, D Chanda, JR Dager, NS Sharma… - Scientific reports, 2018 - nature.com
Asthma is a chronic inflammatory disease process involving the conductive airways of the
human lung. The dysregulated inflammatory response in this disease process may involve …

[PDF][PDF] Spatial mapping of SARS-CoV-2 and H1N1 lung injury identifies differential transcriptional signatures

C Margaroli, P Benson, NS Sharma, MC Madison… - Cell reports …, 2021 - cell.com
Severe SARS-CoV-2 infection often leads to the development of acute respiratory distress
syndrome (ARDS), with profound pulmonary patho-histological changes post-mortem. It is not …

[HTML][HTML] Developmental reprogramming in mesenchymal stromal cells of human subjects with idiopathic pulmonary fibrosis

…, S Rangarajan, M Locy, K Bernard, NS Sharma… - Scientific reports, 2016 - nature.com
Cellular plasticity and de-differentiation are hallmarks of tissue/organ regenerative capacity
in diverse species. Despite a more restricted capacity for regeneration, humans with age-…

[HTML][HTML] Interferon-dependent signaling is critical for viral clearance in airway neutrophils

C Margaroli, T Fram, NS Sharma, SB Patel, J Tipper… - JCI insight, 2023 - ncbi.nlm.nih.gov
Neutrophilic inflammation characterizes several respiratory viral infections, including COVID-19–related
acute respiratory distress syndrome, although its contribution to disease …

[PDF][PDF] Extracorporeal membrane oxygenation in adults: A practical guide for internists

T Kulkarni, NS Sharma, E Diaz-Guzman - Cleve Clin J Med, 2016 - scholar.archive.org
The use of extracorporeal membrane oxygenation (ECMO) in adults has rapidly increased as
the technology has evolved, although there is little definitive evidence that it is beneficial in …

[HTML][HTML] Extracorporeal membrane oxygenation in the pre and post lung transplant period

NS Sharma, MG Hartwig, D Hayes Jr - Annals of translational …, 2017 - ncbi.nlm.nih.gov
Evolution in technology has resulted in rapid increase in utilization of extracorporeal membrane
oxygenation (ECMO) as a bridge to recovery and/or transplantation. Although there is …

Pulmonary and critical care considerations for E-cigarette, or vaping, product use-associated lung injury

…, NS Sharma, NJ Meyer, LS Smith, S Novosad… - Chest, 2022 - Elsevier
Background In 2019, the United States experienced a nationwide outbreak of e-cigarette, or
vaping, product use-associated lung injury (EVALI). More than one-half of these patients …

[HTML][HTML] Differences in airway microbiome and metabolome of single lung transplant recipients

NS Sharma, G Vestal, K Wille, KN Patel, F Cheng… - Respiratory …, 2020 - Springer
Background Recent studies suggest that alterations in lung microbiome are associated with
occurrence of chronic lung diseases and transplant rejection. To investigate the host-…

Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients

NS Sharma, KM Wille, S Athira, D Zhi, KP Hough… - The Journal of Heart and …, 2018 - Elsevier
… Author links open overlay panel Nirmal S. Sharma MD a , Keith M. Wille MD a , … were
distinctive between the 2 airway compartments, Wilcoxon’s signed rank test was used to perform the …