… In fact, extensive efforts in the laboratory of the authors (P. Sung, unpublished observations)
have failed to reveal such an activity. The apparent lack of a recombination mediator activity …

Homologous recombination (HR) is an important mechanism for the repair of damaged
chromosomes, for preventing the demise of damaged replication forks, and for several other …

Through pairing and shuffling of related DNA sequences, homologous recombination (HR)
1 serves to create genetic diversity. In both mitotic and meiotic cells, HR is also an important …

… The population-attributable fraction of chronic kidney disease was defined as P×(HR−1)/(1+P×[HR−1])
where P is the prevalence of chronic kidney disease and HR is the hazard ratio (…

… Polyclonal antibodies against the p-RAD51 fusion protein were raised in rabbits andpurified
with the use of a Sepharose column containing the p-RAD51antigen. Extract(fraction 1) was …

The RAD51 and RAD52 genes of Saccharomyces cerevisiae are key members of
theRAD52 epistasis group required for genetic recombination and the repair of DNA double-stranded …

… at the 3′ or 5′ end with 32 P and then treated the labeled DNA species with purified Rad50…
>70% loss of the 32 P label, whereas little release of the 32 P label was observed with the 5…

… -terminal 116 residues of the p protein, yielding plasmid pR57.2. In these plasmids, the
expression of the p-Rad55 and p-Rad57 hybrid polypeptides is driven by the KP~ promoter. …

… The average percentage of T-SCEs from four independent experiments is shown, with a
p value derived from a two-tailed, unpaired t test. F, Immunoblot showing >90% reduction of …

… To characterize its anti-recombination activity further, Srs2 was added to D-loop reactions
in which pairing of a 32 P-labelled 90-mer oligonucleotide with a homologous duplex target is …