Biological markers of acute lung injury: prognostic and pathogenetic significance.

JF Pittet, RC Mackersie, TR Martin… - American journal of …, 1997 - atsjournals.org
Interest in the pathogenetic mechanisms of acute lung injury has focusd in recent years on
the cellular and biochemical mediators of the acute respiratory distress syndrome (ARDS), …

Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway?

…, MT Ganter, MA Matthay, RC Mackersie… - Annals of …, 2007 - journals.lww.com
Objectives: Coagulopathy following major trauma is conventionally attributed to activation and
consumption of coagulation factors. Recent studies have identified an acute coagulopathy …

Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis

…, MJ Schultz, M Levi, RC Mackersie… - Journal of Trauma …, 2008 - journals.lww.com
Background: Coagulopathy is present at admission in 25% of trauma patients, is associated
with shock and a 5-fold increase in mortality. The coagulopathy has recently been …

The etiology of missed cervical spine injuries

…, DL Phreaner, DB Hoyt, RC Mackersie - Journal of Trauma and …, 1993 - journals.lww.com
Missed or delayed diagnosis of cervical spine (C-spine) injuries may lead to extension of
those injuries and subsequent preventable mortality or morbidity. Previous reports examining …

The epidemiology of traumatic death: a population-based analysis

SR Shackford, RC Mackersie, TL Holbrook… - Archives of …, 1993 - jamanetwork.com
• Despite the proliferation of trauma systems, there are no population-based data describing
the epidemiology of traumatic death. To provide these data, we reviewed all trauma deaths …

Prospective randomized trial of LC+ LCBDE vs ERCP/S+ LC for common bile duct stone disease

…, WP Schecter, AR Campbell, RC Mackersie… - Archives of …, 2010 - jamanetwork.com
Objective To compare outcome parameters for good-risk patients with classic signs,
symptoms, and laboratory and abdominal imaging features of cholecystolithiasis and …

The development of acute lung injury is associated with worse neurologic outcome in patients with severe traumatic brain injury

MC Holland, RC Mackersie, D Morabito… - Journal of Trauma …, 2003 - journals.lww.com
Objective: The purpose of this study was to determine the incidence of acute lung injury (ALI)
in trauma patients with severe traumatic brain injury (TBI), to evaluate the impact of ALI on …

Blunt carotid artery dissection: incidence, associated injuries, screening, and treatment

…, DB HOYT, RC MACKERSIE… - Journal of Trauma …, 1990 - journals.lww.com
Blunt carotid dissection (BCD) is a rare injury occurring in less than one in 1,000 victims of
blunt injuries. Using a 4-year experience in a trauma system with 14 cases of BCD, we …

Venous thromboembolism in patients with major trauma

…, NS Brewer, DB Hoyt, RC Mackersie - The American Journal of …, 1990 - Elsevier
The risk of venous thromboembolism after trauma is thought to be high, but the specific risk
factors and the incidence of venous thromboembolism in the trauma population are poorly …

Base deficit as a guide to volume resuscitation

…, SR Shackford, RC Mackersie… - 50 Landmark Papers …, 2019 - api.taylorfrancis.com
The base deficit (BD) is a potentially useful indicator of volume deficit in trauma patients. To
evaluate BD as an index for fluid resuscitation, the records of 209 trauma patients with serial …