PPARα agonist-induced rodent tumors: modes of action and human relevance

…, JC Cook, JC Corton, RM David… - Critical reviews in …, 2003 - Taylor & Francis
Widely varied chemicals—including certain herbicides, plasticizers, drugs, and natural
products—induce peroxisome proliferation in rodent liver and other tissues. This phenomenon is …

[HTML][HTML] Potential release scenarios for carbon nanotubes used in composites

B Nowack, RM David, H Fissan, H Morris… - Environment …, 2013 - Elsevier
The expected widespread use of carbon nanotube (CNT)-composites in consumer products
calls for an assessment of the possible release and exposure to workers, consumers and …

NTP center for the evaluation of risks to human reproduction reports on phthalates: addressing the data gaps

RH McKee, JH Butala, RM David, G Gans - Reproductive toxicology, 2004 - Elsevier
… Calculated phthalate intake based on the geometric mean values for urinary metabolites
using the method of David [17]. Data are from a population of 2541 individuals, considered to …

[HTML][HTML] Maternal plasma 25-hydroxyvitamin D concentrations and the risk for gestational diabetes mellitus

C Zhang, C Qiu, FB Hu, RM David, RM van Dam… - PloS one, 2008 - journals.plos.org
Background Evidence is accumulating for a role of vitamin D in maintaining normal glucose
homeostasis. However, studies that prospectively examined circulating concentrations of 25-…

Aphasia after stroke: natural history and associated deficits.

DT Wade, RL Hewer, RM David… - Journal of Neurology …, 1986 - jnnp.bmj.com
Data relating to 976 patients registered as suffering an acute stroke has been analysed to
determine the natural history of speech disturbance: these patients came from a community …

A cardiac myosin binding protein C mutation in the Maine Coon cat with familial hypertrophic cardiomyopathy

KM Meurs, X Sanchez, RM David… - Human molecular …, 2005 - academic.oup.com
Hypertrophic cardiomyopathy (HCM) is one of the most common causes of sudden cardiac
death in young adults and is a familial disease in at least 60% of cases. Causative mutations …

Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters

…, JT Thompson, RH McKee, RM David… - Toxicological …, 2004 - academic.oup.com
Administration of phthalates is known to cause toxicity and liver cancer in rodents through
the activation of peroxisome proliferator-activated receptors (PPARs), and the monoesters …

[HTML][HTML] A role for Toll-like receptor 3 variants in host susceptibility to enteroviral myocarditis and dilated cardiomyopathy

…, G Pratt, JLF Bersola, J Varela, RM David… - Journal of Biological …, 2010 - ASBMB
The innate antiviral response is mediated, at least in part, by Toll-like receptors (TLRs).
TLR3 signaling is activated in response to viral infection, and the absence of TLR3 in mice …

Chronic toxicity of di (2-ethylhexyl) phthalate in rats

RM David, MR Moore, DC Finney… - Toxicological …, 2000 - academic.oup.com
Fischer 344 rats were treated with 0, 100, 500, 2500, or 12,500 ppm di(2-ethylhexyl)phthalate
(DEHP) in the diet for up to 104 weeks. Blood and urine were analyzed at weeks 26, 52, 78…

Exposure to phthalate esters.

RM David - Environmental Health Perspectives, 2000 - ehp.niehs.nih.gov
The American Chemistry Council Phthalate Esters Panel read with great interest the paper
by Blount et al.(1) regarding urinary levels of phthalate ester metabolites in a sample set of …