Background: Pulmonary hypertension is a progressive and often fatal complication of the
scleroderma spectrum of disease for which no treatment has been proven effective in a …

Objective: Recent studies suggest an association between chronic cough and gastroesophageal
reflux. Our study aims were 1) to define the prevalence of acid reflux induced cough in …

Study objectives: To assess the efficacy and safety of continuous subcutaneous infusion of
treprostinil, a stable prostacyclin analogue, for treating pulmonary arterial hypertension (PAH) …

Background Small airways dysfunction (SAD) is well recognised in asthma, yet its role in the
severity and control of asthma is unclear. This study aimed to assess which combination of …

Background Although small airway disease is a feature of asthma, its association with
relevant asthma outcomes remains unclear. The ATLANTIS study was designed to identify the …

Background Rare genetic variants cause pulmonary arterial hypertension, but the contribution
of common genetic variation to disease risk and natural history is poorly characterised. …

Background. Infectious complications continue to represent a significant source of morbidity
and mortality in lung transplant recipients. Identifying specific, remediable immune defects is …

Objective Pulmonary hypertension with pathologicalchanges similar to those observed in
primary pulmonary hypertensionoccurs in patients with systemic lupus erythematosus (SLE). …

Background We determined the relative efficacy of subcutaneous (SC) treprostinil in stable
World Health Organization class II and III patients transitioned from IV epoprostenol. Methods …

BACKGROUND: There is a paucity of literature concerning general anesthesia and surgery
in patients with amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). This report …