To the Editor: There is a growing awareness of heterogeneity between patients with OSA in
terms of symptoms and comorbidities. 1 The aim of this study was to identify clinically …

Neutrophils may participate in the development of lung fibrosis. Hepatocyte growth factor (HGF),
a growth factor for type II pneumocytes, is produced by neutrophils. We measured the …

… hypopnea was defined as at least a 30% decrease in the nasal pressure signal combined
with either ≥ 3% arterial oxygen desaturation or an arousal (PSG), both lasting at least 10 s. …

Rationale Chronic intermittent hypoxia occurring in obstructive sleep apnea (OSA) is
independently associated with nonalcoholic fatty liver disease (NAFLD). Chronic obstructive …

We tested the novel hypothesis that neutrophils in the lung or the airspaces may produce
hepatocyte growth factor (HGF) in ventilated patients with acute respiratory failure. Neutrophils …

Obstructive sleep apnea (OSA) may contribute to the development of nonalcoholic fatty liver
disease. We performed a multisite cross-sectional study to evaluate the association between …

Background Home non-invasive ventilation (NIV) is a widely used treatment for chronic
hypoventilation but little is known on its impact in the elderly. In a multicenter prospective cohort …

INTRODUCTION: The alveolar epithelium is the principal target in the course of acute lung
injury (ALI) and the acute respiratory distress syndrome (ARDS) and to a lesser extent in …

… F IO 2 was set to obtain S pO 2 of 88–92%. The decision to intubate and initiate invasive
ventilation was made when any of the following was observed: persistent hypoxemia, severe …

Lymphomatoid granulomatosis is a rare angiocentric and angiodestructive disease, which
commonly involves the lungs but also the brain, kidneys, liver and skin. This report describes …