User profiles for S. Matthes
Stephen G. MatthewsProfessor of Physiology, University of Toronto Verified email at utoronto.ca Cited by 21168 |
Life without brain serotonin: reevaluation of serotonin function with mice deficient in brain serotonin synthesis
…, D Beis, M Pasqualetti, J Waider, S Matthes… - Behavioural brain …, 2015 - Elsevier
… However, [ 35 S]GTP-γ-S binding revealed slightly enhanced labeling only in septum and
frontal cortex [31]. In brain slice recordings of 5-HT neurons, Tph2 −/− mice showed slightly …
frontal cortex [31]. In brain slice recordings of 5-HT neurons, Tph2 −/− mice showed slightly …
Nurturing care: promoting early childhood development
PR Britto, SJ Lye, K Proulx, AK Yousafzai, SG Matthews… - The lancet, 2017 - thelancet.com
The UN Sustainable Development Goals provide a historic opportunity to implement interventions,
at scale, to promote early childhood development. Although the evidence base for the …
at scale, to promote early childhood development. Although the evidence base for the …
Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo …
…, A Koch, G Leuschner, S Matthes… - The Lancet …, 2021 - thelancet.com
Background Pirfenidone has been shown to slow disease progression in patients with
idiopathic pulmonary fibrosis (IPF). However, there are few treatment options for progressive …
idiopathic pulmonary fibrosis (IPF). However, there are few treatment options for progressive …
[HTML][HTML] A comprehensive survey on climate optimal aircraft trajectory planning
…, S Matthes, V Grewe, S Dietmüller, S Baumann… - Aerospace, 2022 - mdpi.com
… To investigate these possibilities, this paper presents a survey on operational strategies
proposed in the literature to mitigate aviation’s climate impact. These approaches are classified …
proposed in the literature to mitigate aviation’s climate impact. These approaches are classified …
Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation
…, AM Cornett, AA Dreffs, SA Matthes… - American journal of …, 2012 - atsjournals.org
Rationale: Extracellular matrix (ECM) is a dynamic tissue that contributes to organ integrity
and function, and its regulation of cell phenotype is a major aspect of cell biology. However, …
and function, and its regulation of cell phenotype is a major aspect of cell biology. However, …
[HTML][HTML] Evaluating the climate impact of aviation emission scenarios towards the Paris agreement including COVID-19 effects
…, B Ohlenforst, S Blakey, S Christie, S Matthes… - Nature …, 2021 - nature.com
… ’s climate impact, though the sector’s contribution to global warming remains considerable.
Contrarily, we find that ICAO’s … considerable contribution to aviation’s climate impact, however…
Contrarily, we find that ICAO’s … considerable contribution to aviation’s climate impact, however…
Multimodel projections of stratospheric ozone in the 21st century
… (60S to 60N), the equatorial region (25S to 25N), the northern midlatitude region (35N to 60N),
and the southern midlatitude region (60S to 35S). … Averaged between 60N and 60S, total …
and the southern midlatitude region (60S to 35S). … Averaged between 60N and 60S, total …
Lrp5 functions in bone to regulate bone mass
…, N Alenina, DR Robinson, Z Zhong, S Matthes… - Nature medicine, 2011 - nature.com
… compression using a crosshead speed of 0.2 mm s −1 , during which we collected force and
displacement measurements every 0.005 s. From the force versus displacement curves, we …
displacement measurements every 0.005 s. From the force versus displacement curves, we …
Earth system chemistry integrated modelling (ESCiMo) with the modular earth submodel system (MESSy) version 2.51
…, B Kern, S Matthes, M Mertens, S Meul… - Geoscientific Model …, 2016 - gmd.copernicus.org
Three types of reference simulations, as recommended by the Chemistry–Climate Model
Initiative (CCMI), have been performed with version 2.51 of the European Centre for Medium-…
Initiative (CCMI), have been performed with version 2.51 of the European Centre for Medium-…
[HTML][HTML] Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin
V Mosienko, B Bert, D Beis, S Matthes, H Fink… - Translational …, 2012 - nature.com
Serotonin is a major neurotransmitter in the central nervous system (CNS). Dysregulation of
serotonin transmission in the CNS is reported to be related to different psychiatric disorders …
serotonin transmission in the CNS is reported to be related to different psychiatric disorders …