In summary, we found that hypercapnia was common in patients with COVID-19–associated
ARDS while using low VT ventilation. VR was increased in these patients, which reflected …

Rationale: Unphysiologic strain (the ratio between tidal volume and functional residual
capacity) and stress (the transpulmonary pressure) can cause ventilator-induced lung damage. …

Purpose To investigate whether COVID-19-ARDS differs from all-cause ARDS. Methods
Thirty-two consecutive, mechanically ventilated COVID-19-ARDS patients were compared to …

Background In ARDS patients, mechanical ventilation should minimize ventilator-induced lung
injury. The mechanical power which is the energy per unit time released to the respiratory …

Importance Data on the association of COVID-19 vaccination with intensive care unit (ICU)
admission and outcomes of patients with SARS-CoV-2–related pneumonia are scarce. …

New evidence suggests that physiological and damaging agents activate two different
pathways of apoptotic signalling, which are mediated by protein-protein interactions and …

Modalities of fluid management in patients sustaining the acute respiratory distress syndrome
(ARDS) are challenging and controversial. Optimal fluid management should provide …

Introduction SARS-CoV-2 might spread through the nervous system, reaching respiratory
centers in the brainstem. Because we recently reported neurophysiological brainstem reflex …

Introduction Patients with acute respiratory failure requiring respiratory support with invasive
mechanical ventilation while awaiting lung transplantation are at a high risk of death. …

ARDS is a life-threatening organ failure due to several pulmonary and extrapulmonary injuries
with an incidence between 5 and 60 cases/100,000 persons/y. Patients with ARDS have …