User profiles for Takeshi Shimizu

Takeshi Shimizu

名古屋市立大学 医学研究科 脳神経生理学
Verified email at med.nagoya-cu.ac.jp
Cited by 1094

[HTML][HTML] Control of cell proliferation and apoptosis by mob as tumor suppressor, mats

ZC Lai, X Wei, T Shimizu, E Ramos, M Rohrbaugh… - Cell, 2005 - cell.com
Appropriate cell number and organ size in a multicellular organism are determined by
coordinated cell growth, proliferation, and apoptosis. Disruption of these processes can cause …

Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila

X Wei, T Shimizu, ZC Lai - The EMBO journal, 2007 - embopress.org
Tissue growth and organ size are determined by coordinated cell proliferation and apoptosis
in development. Recent studies have demonstrated that Hippo (Hpo) signaling plays a …

Japanese early-warning for debris flows and slope failures using rainfall indices with Radial Basis Function Network

N Osanai, T Shimizu, K Kuramoto, S Kojima, T Noro - Landslides, 2010 - Springer
Early-warning systems for natural disasters are important tools for disaster risk reduction and
for achieving sustainable development and livelihoods. In 2005, the Japanese government …

Stabilized β-catenin functions through TCF/LEF proteins and the Notch/RBP-Jκ complex to promote proliferation and suppress differentiation of neural precursor cells

T Shimizu, T Kagawa, T Inoue, A Nonaka… - … and cellular biology, 2008 - Am Soc Microbiol
The proliferation and differentiation of neural precursor cells are mutually exclusive during
brain development. Despite its importance for precursor cell self renewal, the molecular …

In Vivo and In Vitro Effects of Macrolide Antibiotics on Mucus Secretion in Airway Epithelial Cells

T Shimizu, S Shimizu, R Hattori… - American journal of …, 2003 - atsjournals.org
To examine the in vivo effects of macrolide antibiotics on mucus hypersecretion, we induced
hypertrophic and metaplastic changes of goblet cells in rat nasal epithelium by intranasal …

Nanogel DDS enables sustained release of IL-12 for tumor immunotherapy

T Shimizu, T Kishida, U Hasegawa, Y Ueda… - Biochemical and …, 2008 - Elsevier
For a valid cytokine immunotherapy of malignancies, a suitable delivery system that ensures
slow-release of cytokines is required, because short half-life in vivo of the molecules ruins …

[HTML][HTML] Wnt signaling controls the timing of oligodendrocyte development in the spinal cord

T Shimizu, T Kagawa, T Wada, Y Muroyama… - Developmental …, 2005 - Elsevier
During spinal cord development, oligodendrocytes are generated from a restricted region of
the ventral ventricular zone and then spread out into the entire spinal cord. These events are …

Preferential conduction across the ventricular outflow septum in ventricular arrhythmias originating from the aortic sinus cusp

…, Y Murakami, N Yoshida, T Okada, T Shimizu… - Journal of the American …, 2007 - jacc.org
Objectives : The purpose of this study was to examine the relationship between the origin
and breakout site of idiopathic ventricular tachycardia (VT) or premature ventricular …

[HTML][HTML] A multi-site, multi-disorder resting-state magnetic resonance image database

…, H Mano, W Yoshida, B Seymour, T Shimizu… - Scientific data, 2021 - nature.com
Abstract Machine learning classifiers for psychiatric disorders using resting-state functional
magnetic resonance imaging (rs-fMRI) have recently attracted attention as a method for …

Active tactile sensor for detecting contact force and hardness of an object

M Shikida, T Shimizu, K Sato, K Itoigawa - Sensors and Actuators A …, 2003 - Elsevier
We propose a new type of tactile sensor that can detect both the contact force and hardness
of an object. It consists of a diaphragm with a mesa structure, a piezo-resistive displacement …