User profiles for Timothy D Girard

Timothy D. Girard

Professor of Critical Care Medicine, University of Pittsburgh School of Medicine
Verified email at pitt.edu
Cited by 27620

Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled …

TD Girard, JP Kress, BD Fuchs, JWW Thomason… - The Lancet, 2008 - thelancet.com
Background Approaches to removal of sedation and mechanical ventilation for critically ill
patients vary widely. Our aim was to assess a protocol that paired spontaneous awakening …

[HTML][HTML] Long-term cognitive impairment after critical illness

PP Pandharipande, TD Girard… - … England Journal of …, 2013 - Mass Medical Soc
Background Survivors of critical illness often have a prolonged and disabling form of cognitive
impairment that remains inadequately characterized. Methods We enrolled adults with …

Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial

…, BT Pun, DL Herr, M Maze, TD Girard… - Jama, 2007 - jamanetwork.com
ContextLorazepam is currently recommended for sustained sedation of mechanically
ventilated intensive care unit (ICU) patients, but this and other benzodiazepine drugs may …

Delirium as a predictor of long-term cognitive impairment in survivors of critical illness

TD Girard, JC Jackson, PP Pandharipande… - Critical care …, 2010 - journals.lww.com
Objective: To test the hypothesis that duration of delirium in the intensive care unit is an
independent predictor of long-term cognitive impairment after critical illness requiring …

[HTML][HTML] Delirium

…, C Cunningham, Y Shehabi, TD Girard… - Nature Reviews …, 2020 - nature.com
Delirium, a syndrome characterized by an acute change in attention, awareness and
cognition, is caused by a medical condition that cannot be better explained by a pre-existing …

[HTML][HTML] Delirium in the intensive care unit

TD Girard, PP Pandharipande, EW Ely - Critical care, 2008 - Springer
Delirium, an acute and fluctuating disturbance of consciousness and cognition, is a common
manifestation of acute brain dysfunction in critically ill patients, occurring in up to 80% of the …

Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study

…, SJ Peterson, NE Brummel, TD Girard… - The Lancet …, 2021 - thelancet.com
Background To date, 750 000 patients with COVID-19 worldwide have required mechanical
ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). We …

Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the BRAIN-ICU study: a longitudinal cohort study

JC Jackson, PP Pandharipande, TD Girard… - The lancet Respiratory …, 2014 - thelancet.com
Background Critical illness is associated with cognitive impairment, but mental health and
functional disabilities in survivors of intensive care are inadequately characterised. We aimed …

The immunopathogenesis of sepsis in elderly patients

SM Opal, TD Girard, EW Ely - Clinical infectious diseases, 2005 - academic.oup.com
Prominent among the numerous events that contribute to the enhanced susceptibility of
elderly patients to infection is the decline of immune function that accompanies aging. Elderly …

[HTML][HTML] Haloperidol and ziprasidone for treatment of delirium in critical illness

TD Girard, MC Exline, SS Carson… - … England Journal of …, 2018 - Mass Medical Soc
Background There are conflicting data on the effects of antipsychotic medications on delirium
in patients in the intensive care unit (ICU). Methods In a randomized, double-blind, placebo…