User profiles for Timothy D Girard
Timothy D. GirardProfessor of Critical Care Medicine, University of Pittsburgh School of Medicine Verified email at pitt.edu Cited by 27620 |
Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled …
TD Girard, JP Kress, BD Fuchs, JWW Thomason… - The Lancet, 2008 - thelancet.com
Background Approaches to removal of sedation and mechanical ventilation for critically ill
patients vary widely. Our aim was to assess a protocol that paired spontaneous awakening …
patients vary widely. Our aim was to assess a protocol that paired spontaneous awakening …
[HTML][HTML] Long-term cognitive impairment after critical illness
PP Pandharipande, TD Girard… - … England Journal of …, 2013 - Mass Medical Soc
Background Survivors of critical illness often have a prolonged and disabling form of cognitive
impairment that remains inadequately characterized. Methods We enrolled adults with …
impairment that remains inadequately characterized. Methods We enrolled adults with …
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial
ContextLorazepam is currently recommended for sustained sedation of mechanically
ventilated intensive care unit (ICU) patients, but this and other benzodiazepine drugs may …
ventilated intensive care unit (ICU) patients, but this and other benzodiazepine drugs may …
Delirium as a predictor of long-term cognitive impairment in survivors of critical illness
TD Girard, JC Jackson, PP Pandharipande… - Critical care …, 2010 - journals.lww.com
Objective: To test the hypothesis that duration of delirium in the intensive care unit is an
independent predictor of long-term cognitive impairment after critical illness requiring …
independent predictor of long-term cognitive impairment after critical illness requiring …
[HTML][HTML] Delirium
Delirium, a syndrome characterized by an acute change in attention, awareness and
cognition, is caused by a medical condition that cannot be better explained by a pre-existing …
cognition, is caused by a medical condition that cannot be better explained by a pre-existing …
[HTML][HTML] Delirium in the intensive care unit
Delirium, an acute and fluctuating disturbance of consciousness and cognition, is a common
manifestation of acute brain dysfunction in critically ill patients, occurring in up to 80% of the …
manifestation of acute brain dysfunction in critically ill patients, occurring in up to 80% of the …
Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study
…, SJ Peterson, NE Brummel, TD Girard… - The Lancet …, 2021 - thelancet.com
Background To date, 750 000 patients with COVID-19 worldwide have required mechanical
ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). We …
ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). We …
Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the BRAIN-ICU study: a longitudinal cohort study
JC Jackson, PP Pandharipande, TD Girard… - The lancet Respiratory …, 2014 - thelancet.com
Background Critical illness is associated with cognitive impairment, but mental health and
functional disabilities in survivors of intensive care are inadequately characterised. We aimed …
functional disabilities in survivors of intensive care are inadequately characterised. We aimed …
The immunopathogenesis of sepsis in elderly patients
Prominent among the numerous events that contribute to the enhanced susceptibility of
elderly patients to infection is the decline of immune function that accompanies aging. Elderly …
elderly patients to infection is the decline of immune function that accompanies aging. Elderly …
[HTML][HTML] Haloperidol and ziprasidone for treatment of delirium in critical illness
TD Girard, MC Exline, SS Carson… - … England Journal of …, 2018 - Mass Medical Soc
Background There are conflicting data on the effects of antipsychotic medications on delirium
in patients in the intensive care unit (ICU). Methods In a randomized, double-blind, placebo…
in patients in the intensive care unit (ICU). Methods In a randomized, double-blind, placebo…