An increased expression of members of the matrix metalloproteinase (MMP) family of enzymes
is seen in almost every human tissue in which inflammation is present. Through the use …

Acute lung injury (ALI) is a clinical disease marked by respiratory failure due to disruption of
the epithelial and endothelial barrier, flooding of the alveolar compartment with protein-rich …

Several studies have implicated a causative role for specific matrix metalloproteinases (MMPs)
in the development and progression of cigarette smoke-induced chronic obstructive …

Macrophages are key orchestrators of the inflammatory and repair responses in the lung,
and the diversity of their function is indicated by their polarized states and distinct …

Advancements in methods, technology, and our understanding of the pathobiology of lung
injury have created the need to update the definition of experimental acute lung injury (ALI). …

Rationale: Matrix metalloproteinase (MMP)-28 regulates the inflammatory and extracellular
matrix responses in cardiac aging, but the roles of MMP-28 after myocardial infarction (MI) …

Members of the MMP family function in various processes of innate immunity, particularly in
controlling important steps in leukocyte trafficking and activation. MMP28 (epilysin) is a …

Several members of the matrix metalloproteinase (MMP) family control a range of immune
processes, such as leukocyte influx and chemokine activity. Stromelysin-2 (MMP10) is …

… BMDM were incubated in RPMI 1640 containing 5 μg/ml calcein AM (Molecular Probes)
and then washed and suspended at 4 × 10 6 cells/ml in phenol red-free RPMI 1640 (Sigma-…

… This study provides the first genome-wide assessment of serial AM transcriptional … AM
phenotypic states are associated with distinct phases of ARDS, human studies characterizing AM …