Cystic fibrosis pulmonary guidelines: airway clearance therapies

PA Flume, KA Robinson, BP O'Sullivan, JD Finder… - Respiratory …, 2009 - rc.rcjournal.com
Cystic fibrosis (CF) is a genetic disease characterized by dehydration of airway surface liquid
and impaired mucociliary clearance. As a result, there is difficulty clearing pathogens from …

Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health

PA Flume, BP O'Sullivan, KA Robinson… - American journal of …, 2007 - atsjournals.org
Rationale: Cystic fibrosis is a recessive genetic disease characterized by dehydration of the
airway surface liquid and impaired mucociliary clearance. As a result, individuals with the …

[HTML][HTML] Association of cystic fibrosis with abnormalities in fatty acid metabolism

…, M Laposata, JG Alvarez, BP O'Sullivan - … England Journal of …, 2004 - Mass Medical Soc
Background Patients with cystic fibrosis have altered levels of plasma fatty acids. We
previously demonstrated that arachidonic acid levels are increased and docosahexaenoic acid …

The inflammatory role of platelets in cystic fibrosis

BP O'Sullivan, AD Michelson - … journal of respiratory and critical care …, 2006 - atsjournals.org
O'Sullivan and coworkers (47) showed that washed platelets … O'Sullivan and coworkers
(47) also observed a decreased … As discussed above, O'Sullivan and coworkers (47) …

Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel …

…, JP Clancy, A Genatossio, BP O'Sullivan… - The Lancet …, 2023 - thelancet.com
Background Reducing treatment burden is a priority for people with cystic fibrosis, whose
health has benefited from using new modulators that substantially increase CFTR protein …

Obesity‐related asthma in children: A role for vitamin D

BP O'Sullivan, L James, JM Majure… - Pediatric …, 2021 - Wiley Online Library
O'Sullivan and Jessica Snowden: lead conception and drafting of the work; final approval
of the version published. Laura James and Joseph M. Majure: substantial contribution to the …

Population-based newborn screening for genetic disorders when multiple mutation DNA testing is incorporated: a cystic fibrosis newborn screening model …

…, R Gerstle, K Haver, A Lapey, BP O'Sullivan… - …, 2004 - publications.aap.org
Objectives. Newborn screening for cystic fibrosis (CF) provides a model to investigate the
implications of applying multiple-mutation DNA testing in screening for any disorder in a …

Guidelines for implementation of cystic fibrosis newborn screening programs: Cystic Fibrosis Foundation workshop report

…, MK Sontag, J Massie, PM Farrell, BP O'Sullivan - …, 2007 - publications.aap.org
Newborn screening for cystic fibrosis offers the opportunity for early intervention and improved
outcomes. This summary, resulting from a workshop sponsored by the Cystic Fibrosis …

Tracheal bronchus: a cause of prolonged atelectasis in intubated children

BP O'Sullivan, JJ Frassica, SM Rayder - Chest, 1998 - Elsevier
Tracheal bronchus is a common anomaly that occurs in approximately 2% of people. Two
children with multiple medical problems which led to endotracheal intubation are described. …

Interleukin 8 secretion from monocytes of subjects heterozygous for the ΔF508 cystic fibrosis transmembrane conductance regulator gene mutation is altered

…, JC Shea, C Kelly, BP O'Sullivan… - Clinical and Vaccine …, 2004 - Am Soc Microbiol
Patients with cystic fibrosis (CF) exhibit an excessive host inflammatory response. The aim
of this study was to determine (i) whether interleukin 8 (IL-8) secretion is increased from …