[HTML][HTML] Bench-to-bedside review: sepsis is a disease of the microcirculation

PE Spronk, DF Zandstra, C Ince - Critical care, 2004 - Springer
Microcirculatory perfusion is disturbed in sepsis. Recent research has shown that maintaining
systemic blood pressure is associated with inadequate perfusion of the microcirculation in …

[HTML][HTML] Increased mortality associated with growth hormone treatment in critically ill adults

…, NR Webster, MS Nielsen, DF Zandstra… - … England Journal of …, 1999 - Mass Medical Soc
Background The administration of growth hormone can attenuate the catabolic response to
injury, surgery, and sepsis. However, the effect of high doses of growth hormone on the …

The effect of selective decontamination of the digestive tract on colonisation and infection rate in multiple trauma patients

…, HKF Van Saene, DR Miranda, DF Zandstra - Intensive care …, 1984 - Springer
122 multiple trauma patients staying in the ICU for 5 or more days and needing mechanical
ventilation were investigated to determine the effect of selective decontamination of the …

Effects of early high-volume continuous venovenous hemofiltration on survival and recovery of renal function in intensive care patients with acute renal failure: a …

…, JGP Tijssen, DF Zandstra… - Critical care …, 2002 - journals.lww.com
Objective To study the effects of the initiation time of continuous venovenous hemofiltration
and of the ultrafiltrate rate in patients with circulatory and respiratory insufficiency developing …

Nitroglycerin in septic shock after intravascular volume resuscitation

…, HM Oudemans-van Straaten, DF Zandstra - The lancet, 2002 - thelancet.com
… C Ince, HM Oudemans-van Straaten, and DF Zandstra conceived the idea about vasodilation
in sepsis. KR Mathura … C Ince and DF Zandstra measured flow parameters from the images. …

Impact of selective decontamination of the digestive tract on multiple organ dysfunction syndrome: systematic review of randomized controlled trials

L Silvestri, HKF van Saene, DF Zandstra… - Critical care …, 2010 - journals.lww.com
… We also evaluated I 2 with the formula 100% × (Q − df) / Q, where Q is Cochran Q statistic
and df is the degree of freedom (number of studies − 1). Negative values of I 2 are equal to 0%; …

Glucose variability is associated with intensive care unit mortality

…, TM Vriesendorp, RJ Bosman, DF Zandstra… - Critical care …, 2010 - journals.lww.com
Objective: Mounting evidence suggests a role for glucose variability in predicting intensive
care unit (ICU) mortality. We investigated the association between glucose variability and …

Plasma glutamine depletion and patient outcome in acute ICU admissions

…, M Treskes, HJI Van der Spoel, DF Zandstra - Intensive care …, 2001 - Springer
Objective: To evaluate whether low plasma glutamine (PG) is related to severity of illness,
and actual and predicted hospital mortality. Design: Prospective cohort study. Setting: 18-bed …

Prognosis of coma after therapeutic hypothermia: a prospective cohort study

…, MA Kuiper, FH Bosch, DF Zandstra… - Annals of …, 2012 - Wiley Online Library
Objective: This study was designed to establish the reliability of neurologic examination,
neuron‐specific enolase (NSE), and median nerve somatosensory‐evoked potentials (SEPs) to …

Citrate anticoagulation for continuous venovenous hemofiltration

…, JI Van Der Spoel, LM Dijksman, DF Zandstra - Critical care …, 2009 - journals.lww.com
Objective: Continuous venovenous hemofiltration (CVVH) is applied in critically ill patients
with acute renal failure for renal replacement. Heparins used to prevent circuit clotting may …