Importance Experimental data suggest that intravenous vitamin C may attenuate inflammation
and vascular injury associated with sepsis and acute respiratory distress syndrome (ARDS…

BACKGROUND & AIMS: The 7α-dehydroxylation of primary bile acids (BAs), chenodeoxycholic
(CDCA) and cholic acid (CA) into the secondary BAs, lithocholic (LCA) and deoxycholic …

Hepatic encephalopathy (HE) has been related to gut bacteria and inflammation in the setting
of intestinal barrier dysfunction. We aimed to link the gut microbiome with cognition and …

Recurrent hepatic encephalopathy (HE) is a leading cause of readmission despite standard
of care (SOC) associated with microbial dysbiosis. Fecal microbiota transplantation (FMT) …

Infections worsen survival in cirrhosis; however, simple predictors of survival in infection‐related
acute‐on‐chronic liver failure (I‐ACLF) derived from multicenter studies are required in …

Background: As ongoing research explores the impact of moral distress on health care
professionals (HCPs) and organizations and seeks to develop effective interventions, valid and …

Bacterial infections are an important cause of mortality in cirrhosis, but there is a paucity of
multicenter studies. The aim was to define factors predisposing to infection‐related mortality in …

Background Safety of individual probiotic strains approved under Investigational New Drug
( IND ) policies in cirrhosis with minimal hepatic encephalopathy ( MHE ) is not clear. Aim …

… Bajaj, Jasmohan S MD, MS 1 ; Wade, James B PhD 2 ; Gibson, Douglas P PsyD, MPH 2 ;
Heuman, Douglas M MD 1 ; Thacker, Leroy R … Thacker was involved in the statistical analysis. …

Altered gut microbiome is associated with systemic inflammation and cirrhosis decompensation.
However, the correlation of the oral microbiome with inflammation in cirrhosis is unclear. …