User profiles for L. R. Thacker
Leroy ThackerVCU - Department of Biostatistics Verified email at vcu.edu Cited by 13662 |
Effect of vitamin C infusion on organ failure and biomarkers of inflammation and vascular injury in patients with sepsis and severe acute respiratory failure: the CITRIS …
Importance Experimental data suggest that intravenous vitamin C may attenuate inflammation
and vascular injury associated with sepsis and acute respiratory distress syndrome (ARDS…
and vascular injury associated with sepsis and acute respiratory distress syndrome (ARDS…
Modulation of the fecal bile acid profile by gut microbiota in cirrhosis
…, NA Noble, P Monteith, M Fuchs, LR Thacker… - Journal of …, 2013 - Elsevier
BACKGROUND & AIMS: The 7α-dehydroxylation of primary bile acids (BAs), chenodeoxycholic
(CDCA) and cholic acid (CA) into the secondary BAs, lithocholic (LCA) and deoxycholic …
(CDCA) and cholic acid (CA) into the secondary BAs, lithocholic (LCA) and deoxycholic …
Linkage of gut microbiome with cognition in hepatic encephalopathy
…, JM Ridlon, PB Hylemon, LR Thacker… - American Journal …, 2012 - journals.physiology.org
Hepatic encephalopathy (HE) has been related to gut bacteria and inflammation in the setting
of intestinal barrier dysfunction. We aimed to link the gut microbiome with cognition and …
of intestinal barrier dysfunction. We aimed to link the gut microbiome with cognition and …
[PDF][PDF] Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: a randomized clinical trial
Recurrent hepatic encephalopathy (HE) is a leading cause of readmission despite standard
of care (SOC) associated with microbial dysbiosis. Fecal microbiota transplantation (FMT) …
of care (SOC) associated with microbial dysbiosis. Fecal microbiota transplantation (FMT) …
[PDF][PDF] Survival in infection‐related acute‐on‐chronic liver failure is defined by extrahepatic organ failures
…, R Malik, RM Subramanian, LR Thacker… - …, 2014 - Wiley Online Library
Infections worsen survival in cirrhosis; however, simple predictors of survival in infection‐related
acute‐on‐chronic liver failure (I‐ACLF) derived from multicenter studies are required in …
acute‐on‐chronic liver failure (I‐ACLF) derived from multicenter studies are required in …
Enhancing understanding of moral distress: the measure of moral distress for health care professionals
…, C Prompahakul, LR Thacker… - AJOB empirical …, 2019 - Taylor & Francis
Background: As ongoing research explores the impact of moral distress on health care
professionals (HCPs) and organizations and seeks to develop effective interventions, valid and …
professionals (HCPs) and organizations and seeks to develop effective interventions, valid and …
[PDF][PDF] Second infections independently increase mortality in hospitalized patients with cirrhosis: the North American consortium for the study of end‐stage liver …
…, G Brown, NA Noble, LR Thacker… - …, 2012 - Wiley Online Library
Bacterial infections are an important cause of mortality in cirrhosis, but there is a paucity of
multicenter studies. The aim was to define factors predisposing to infection‐related mortality in …
multicenter studies. The aim was to define factors predisposing to infection‐related mortality in …
Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis
…, MS Siddiqui, M Fuchs, LR Thacker… - Alimentary …, 2014 - Wiley Online Library
Background Safety of individual probiotic strains approved under Investigational New Drug
( IND ) policies in cirrhosis with minimal hepatic encephalopathy ( MHE ) is not clear. Aim …
( IND ) policies in cirrhosis with minimal hepatic encephalopathy ( MHE ) is not clear. Aim …
The multi-dimensional burden of cirrhosis and hepatic encephalopathy on patients and caregivers
…, DP Gibson, DM Heuman, LR Thacker… - Official journal of the …, 2011 - journals.lww.com
… Bajaj, Jasmohan S MD, MS 1 ; Wade, James B PhD 2 ; Gibson, Douglas P PsyD, MPH 2 ;
Heuman, Douglas M MD 1 ; Thacker, Leroy R … Thacker was involved in the statistical analysis. …
Heuman, Douglas M MD 1 ; Thacker, Leroy R … Thacker was involved in the statistical analysis. …
[PDF][PDF] Salivary microbiota reflects changes in gut microbiota in cirrhosis with hepatic encephalopathy
…, K Daita, MB White, A Unser, LR Thacker… - …, 2015 - Wiley Online Library
Altered gut microbiome is associated with systemic inflammation and cirrhosis decompensation.
However, the correlation of the oral microbiome with inflammation in cirrhosis is unclear. …
However, the correlation of the oral microbiome with inflammation in cirrhosis is unclear. …