Immunotherapy is among the most rapidly evolving treatment strategies in oncology. The
therapeutic potential of immune-checkpoint inhibitors is exemplified by the recent hail of Food …

Triple negative breast cancer (TNBC) accounts for 10–20% of cases in breast cancer. Despite
recent advances in the treatment of hormonal receptor+ and HER2+ breast cancers, there …

Apitz-Castro et al. 4a reported that 2-vinyl-4//-1, 3-dithiin (7) and an unknown compound,
now named ajoene, 4b are potent anti-thrombotic agents derived from garlic extract. Unlike …

Using an ORF kinome screen in MCF-7 cells treated with the CDK4/6 inhibitor ribociclib
plus fulvestrant, we identified FGFR1 as a mechanism of drug resistance. FGFR1-amplified/ER+ …

We studied the effect of the methanol extract of garlic bulbs (EOG) and of three pure
components isolated from it (F1, F2, F3), on human platelet aggreggation induced by ADP, …

Infected animals will produce reactive oxygen species (ROS) and other inflammatory molecules
that help fight pathogens, but can inadvertently damage host tissue. Therefore specific …

… We demonstrate the highest-resolution MR images ever obtained of the mouse brain. The
diffusion tensor images (DTI) @ 15 μm spatial resolution are 1,000 times the resolution of most …

Background A very limited amount of research has examined intermittent fasting (IF) programs,
such as time-restricted feeding (TRF), in active populations. Objective Our objective was …

The Gram-positive bacterium Enterococcus faecalis and the fungus Candida albicans are
both found as commensals in many of the same niches of the human body, such as the oral …

The ethanolamine utilization (eut) locus of Enterococcus faecalis, containing at least 19 genes
distributed over four polycistronic messenger RNAs, appears to be regulated by a single …