User profiles for M. Damarla

Mahendra Damarla

Associate Professor of Medicine, Johns Hopkins University
Verified email at jhmi.edu
Cited by 1514

Xanthine oxidoreductase in respiratory and cardiovascular disorders

A Boueiz, M Damarla… - American Journal of …, 2008 - journals.physiology.org
In addition to its critical role in purine metabolism, xanthine oxidoreductase (XOR) has been
implicated in the development of tissue oxidative damage in a wide variety of respiratory …

[HTML][HTML] Prone positioning of nonintubated patients with COVID-19

M Damarla, S Zaeh, S Niedermeyer… - American journal of …, 2020 - atsjournals.org
… Mahendra Damarla … Mahendra Damarla … Sun Q, Qiu H, Huang M, Yang Y. Lower mortality
of COVID-19 by early recognition and intervention: experience from Jiangsu Province. Ann …

Discrepancy in the use of confirmatory tests in patients hospitalized with the diagnosis of chronic obstructive pulmonary disease or congestive heart failure

M Damarla, BR Celli, HX Mullerova… - Respiratory care, 2006 - rc.rcjournal.com
OBJECTIVE: To determine the prevalence of confirmatory use of spirometry in patients
admitted to a tertiary-care facility with the diagnosis of chronic obstructive pulmonary disease (…

[HTML][HTML] IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function

…, O Laeyendecker, BT Garibaldi, L Gao, M Damarla… - JCI insight, 2022 - ncbi.nlm.nih.gov
Background Some clinical features of severe COVID-19 represent blood vessel damage
induced by activation of host immune responses initiated by the coronavirus SARS-CoV-2. We …

The use of analgesia and sedation in mechanically ventilated patients with COVID-19 acute respiratory distress syndrome

…, NM Punjabi, T Siddharthan, M Damarla - Anesthesia & …, 2020 - journals.lww.com
METHODS We included the first 24 adult patients with confirmed severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) admitted to the Johns Hopkins Hospital (JHH) Medical …

[HTML][HTML] Reactive oxygen species induced Ca2+ influx via TRPV4 and microvascular endothelial dysfunction in the SU5416/hypoxia model of pulmonary arterial …

…, C Kliment, J Huetsch, M Damarla… - … of Physiology-Lung …, 2018 - journals.physiology.org
Pulmonary arterial hypertension (PAH) is a lethal disease characterized by elevations in
pulmonary arterial pressure, in part due to formation of occlusive lesions in the distal arterioles …

Discovery of Pyrano[3,4-b]indoles as Potent and Selective HCV NS5B Polymerase Inhibitors

…, G Krishnamurthy, M Damarla… - Journal of medicinal …, 2004 - ACS Publications
… Thin-layer chromatography (TLC) was performed on Analtech silica gel GHLF 250 M
prescored plates. The terms “concentrated” and “evaporated” refer to removal of solvents …

p53 mediates cigarette smoke–induced apoptosis of pulmonary endothelial cells: inhibitory effects of macrophage migration inhibitor factor

…, Z Tekeste, H Amankwan, M Damarla… - American journal of …, 2011 - atsjournals.org
Exposure to cigarette smoke (CS) is the most common cause of emphysema, a debilitating
pulmonary disease histopathologically characterized by the irreversible destruction of lung …

[HTML][HTML] Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury

M Damarla, E Hasan, A Boueiz, A Le, HH Pae… - PloS one, 2009 - journals.plos.org
Mechanical ventilation, a fundamental therapy for acute lung injury, worsens pulmonary
vascular permeability by exacting mechanical stress on various components of the respiratory …

Flow-cytometric method for simultaneous analysis of mouse lung epithelial, endothelial, and hematopoietic lineage cells

…, P Mandke, L Johnston, M Damarla - … of Physiology-Lung …, 2016 - journals.physiology.org
… in a hemocytometer by an investigator blinded to the experimental condition (M. Damarla). …
, Suzuki S, Yamada M, Takahashi T, He M, Suzuki T, Kondo T, Yamaya M. A novel method for …