The mechanisms and pathways of the sensation of dyspnea are incompletely understood,
but recent studies have provided some clarification. Studies of patients with cord transection …

… Financial/nonfinancial disclosures: The authors have reported to CHEST the following
conflicts of interest: Dr Burki is a consultant and medical director for ALung Technologies Inc. Drs …

Chronic eosinophilic pneumonia (CEP) is a disease of unknown cause. The hallmark of CEP
is eosinophil accumulation in the lungs. While the triggering factor is unknown, eosinophil …

In morbid obesity, there is an increased hindrance to breathing caused by the effects of the
increased mass on the chest wall and abdomen; subjects with morbid obesity can maintain …

… symptoms such as chest tightness, shortness of breath, increased urge to breathe,
burning sensation in the chest and throat; preliminary studies by NK Burki, M. Alan, and L.-Y. …

In a series of studies carried out in different experimental models, we investigated the type(s)
of lung afferents and mechanism(s) underlying the cigarette smoke-induced airway …

Dyspnea, an unpleasant sensation of difficulty in breathing, is a common accompaniment of
cardiopulmonary disease. The underlying mechanisms generating this sensation are not …

We have compared the relative value of various techniques used in association with fiberoptic
broncho scopy for the diagnosis of lung cancer. We analyzed the results in 114 patients …

To determine whether nicotine is involved in evoking the irritant effects of cigarette smoke in
airways, we studied the responses to inhalation of a single puff (30 ml) of three types of …

The ability to detect resistive loads added to inspiration was assessed in normal and
asthmatic subjects. The threshold of detection of added loads was higher in the asthmatic (mean …