Respiratory medicines for children: current evidence, unlicensed use and research priorities

…, H Vyas, A Warris, PJ Merkus - European …, 2010 - Eur Respiratory Soc
This European Respiratory Society task force has reviewed the evidence for paediatric
medicines in respiratory disease occurring in adults and children. We describe off-licence use, …

Monitoring childhood asthma: web-based diaries and the asthma control test

…, D Caudri, JC de Jongste, PJ Merkus… - Journal of allergy and …, 2014 - Elsevier
Background Data from asthma diaries are frequently used as an end point in asthma studies;
however, data on the validity of Web-based diaries are scarce. Objectives First, we …

Monitoring strategies in children with asthma: a randomised controlled trial

…, NJ van den Berg, WC Hop, JC de Jongste, PJ Merkus… - Thorax, 2015 - thorax.bmj.com
Background Asthma guidelines recommend monitoring of asthma control. However, in a
substantial proportion of children, asthma is poorly controlled and the best monitoring strategy …

Growth of airways and air spaces in teenagers is related to sex but not to symptoms

PJ Merkus, GJ Borsboom, W Van Pelt… - Journal of Applied …, 1993 - journals.physiology.org
To determine growth patterns of the lung and airways in adolescents, we analyzed maximal
expiratory flow-volume curves, closing capacity, and residual volume. They were obtained …

Assessment of bronchodilator response in children with asthma. Dutch CNSLD Study Group

HJ Waalkens, PJ Merkus… - European …, 1993 - Eur Respiratory Soc
The bronchodilator response (BDR) in forced expiratory volume in one second (FEV1) is
routinely assessed to estimate the reversibility of airways obstruction. However, there is no …

Cost-effectiveness of FENO-based and web-based monitoring in paediatric asthma management: a randomised controlled trial

…, NJ van den Berg, JC de Jongste, PJ Merkus… - Thorax, 2016 - thorax.bmj.com
Background In children with asthma, web-based monitoring and inflammation-driven therapy
may lead to improved asthma control and reduction in medications. However, the cost-…

Computed tomographic estimation of lung dimensions throughout the growth period

…, FR Long, JC Wong, PJ Merkus… - European …, 2006 - Eur Respiratory Soc
The aim of the current study was to use computed tomography (CT) to estimate airway wall
and lumen, and arterial and parenchyma dimensions in children throughout the growth period…

Clinical relevance of Scedosporium spp. and Exophiala dermatitidis in patients with cystic fibrosis: A nationwide study

…, PE Verweij, JF Meis, PJ Merkus - Medical …, 2020 - academic.oup.com
An increased prevalence of various filamentous fungi in sputum samples of patients with cystic
fibrosis (CF) has been reported. The clinical significance, however, is mostly unclear. The …

Estimation of lung growth using computed tomography

…, Y Nakano, MH Lequin, PJ Merkus… - European …, 2003 - Eur Respiratory Soc
Anatomical studies suggest that normal lungs grow by rapid alveolar addition until about 2
yrs of age followed by a gradual increase in alveolar dimensions. The aim of this study was to …

Changes of nebulizer output over the years

PJ Merkus, EE van Essen-Zandvliet… - European …, 1992 - Eur Respiratory Soc
The effects of long-term use and of cleaning on the output of 30 specimens of DeVilbiss 646
nebulizers were investigated in order to assess their influence on outcome and …