Cystic fibrosis (CF) is a genetic disease characterized by dehydration of airway surface liquid
and impaired mucociliary clearance. As a result, there is difficulty clearing pathogens from …

Rationale: Cystic fibrosis is a recessive genetic disease characterized by dehydration of the
airway surface liquid and impaired mucociliary clearance. As a result, individuals with the …

Pulmonary hypertension is a frequent hemodynamic complication associated with a wide
variety of respiratory systems disorders whose only common physiologic abnormalities are …

Respiratory system complications and abnormalities are common in patients with amyotrophic
lateral sclerosis (ALS) and respiratory failure remains the most common cause of death. …

Objective: To develop and validate an equation to predict dead space to tidal volume ratio (V
d/V t) from clinically available data in critically ill mechanically ventilated patients. Design: …

Respiratory complications are common in patients with amyotrophic lateral sclerosis (ALS)
with respiratory failure representing the most common cause of death. Ineffective airway …

Bovine pulmonary endothelial cells grown in vitro were shown to release a factor that was
mitogenic for pulmonary smooth muscle cells during exposure to a reduced oxygen tension …

Exposure of cultured bovine pulmonary artery endothelial cells to varying levels of hypoxia (10%
or 0% O 2 ) for 4 hours resulted in a significant dose-dependent inhibition in endothelial …

Background Cystic fibrosis (CF) is a monogenetic autosomal recessive multi-organ disease
affecting approximately 50,000 patients worldwide. Overall median survival is continually …

The development of pulmonary hypertension in a wide variety of human disease states and
experimental animal models characterized by chronic alveolar hypoxia is mediated by two …