Pulmonary disease is the most important cause of morbidity in preterm neonates, whose
lungs are often physiologically and morphologically immature. Surfactant deficiency in …

Background Population and study design heterogeneity has confounded previous meta-analyses,
leading to uncertainty about effectiveness and safety of elective high-frequency …

Background Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth.
Very different models using clinical parameters at an early postnatal age to predict BPD …

Background Bronchopulmonary dysplasia in premature infants is associated with prolonged
hospitalization, as well as abnormal pulmonary and neurodevelopmental outcome. In …

Background The efficacy and safety of early high-frequency oscillatory ventilation as compared
with conventional synchronized intermittent mandatory ventilation for the treatment of …

Background High-dose erythropoietin has been shown to have a neuroprotective effect in
preclinical models of neonatal brain injury, and phase 2 trials have suggested possible efficacy…

Acute respiratory distress syndrome (ARDS) is undefined in neonates, despite the long-standing
existing formal recognition of ARDS syndrome in later life. We describe the Neonatal …

… ΔV L (mean ± standard error [SE]) was significantly greater with variable-flow compared
with constant-flow NCPAP (P < .001) and was associated with increased C L (mean ± SE). C L …

Objective. To determine whether lung volume changes and breathing pattern parameters
differ among 3 devices for delivery of nasal continuous positive airway pressure (CPAP) in …

Continuous positive airway pressure (CPAP) and noninvasive ventilation (NIV) hold much
promise as means to protect the lungs of newborn infants who have respiratory distress from …