Abstract
We have developed a conceptual and mathematical model for nebulizer performance that attempts to provide a unifying theoretical framework for subsequent in vitro studies. Specifically, we have created a lexicon and a way to describe the effects of a standardized breathing pattern for evaluating small-volume jet nebulizers. This model should help researchers communicate more clearly and study planners to design experiments whose data may be more comparable and thus amenable to meta-analysis.
Footnotes
- Correspondence: Robert L Chatburn RRT-NPS FAARC, Respiratory Therapy, M-56, Cleveland Clinic, 9500 Euclid Avenue, Cleveland OH 44195. E-mail: chatbur{at}ccf.org.
Michael McPeck RRT FAARC is an employee and officer of Healthline Medical and Medi/Nuclear, which are sister corporations that manufacture aerosol drug delivery systems and devices for respiratory therapy and nuclear medicine.
Robert L Chatburn RRT-NPS FAARC reports no conflicts of interest related to the content of this paper.
- Copyright © 2007 by Daedalus Enterprises Inc.
