Article Figures & Data
Figures
- Fig. 1.
Nitric oxide (NO) activates guanylate cyclase, which converts into cyclic guanine monophosphate (cGMP). The presence of cGMP at the smooth muscle causes relaxation. NOS = NO synthase. ACh = acetylcholine. PA = pulmonary artery. Hb = hemoglobin. met Hb = methemoglobin. LA = left atrium. (From Reference 6, with permission.)
- Fig. 2.
Cardiopulmonary interactions during persistent pulmonary hypertension of the newborn. PVR = pulmonary vascular resistance. SVR = systemic vascular resistance. (Adapted from Reference 8, with permission.)
- Fig. 3.
Change in pulmonary artery pressure, from baseline, in postoperative patients who received inhaled nitric oxide (INO) versus placebo. (Adapted from Reference 19, with permission.)
- Fig. 4.
Representative inhaled nitric oxide (INO) weaning protocol. ABG = arterial blood gas. (Adapted from Reference 19, with permission.)
- Fig. 5.
Carbon monoxide (CO) signal transduction pathways. sGC = soluble guanylate cyclase. MAPK = mitogenactivated protein kinase. NO = nitric oxide. cGMP = cyclic guanine monophosphate. HSF = heat shock factor. HSP = heat shock protein. NFκB = nuclear factor-κB. (Adapted from Reference 93, with permission.)
- Fig. 6.
A: The Covox DS delivery system for inhaled carbon monoxide. Covox (carbon monoxide for inhalation) and Covox DS are an Investigational Drug and Device, respectively, and are limited by Federal law to investigational use. B: Carbon monoxide concentration with the Covox DS delivery system. (Courtesy of Ikaria.)
