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Research ArticleConference Proceedings

Definitions and Epidemiology of the Chronically Critically Ill

Shannon S Carson
Respiratory Care June 2012, 57 (6) 848-858; DOI: https://doi.org/10.4187/respcare.01736
Shannon S Carson
Division of Pulmonary and Critical Care Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
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    Fig. 1.

    Schematic comparing commonly used definitions for chronic critical illness. Comparisons are based upon the point of demarcation of CCI relative to days of mechanical ventilation.

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    Fig. 2.

    Relationship between chronic critical illness (CCI), prolonged mechanical ventilation (PMV), and long-term mechanical ventilation. Most CCI patients require PMV, but not all patients meeting various definitions of PMV would necessarily meet clinical definitions of CCI. Similarly, patients with single organ dysfunction requiring long-term or home ventilation, such as patients with neuromuscular diseases, are unique and relatively few. Most clinical studies of CCI or PMV exclude those patients.

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    Fig. 3.

    Incidence rate of tracheostomy for prolonged mechanical ventilation (PMV) per 100,000 population and proportion of mechanically ventilated patients who received a tracheostomy over 10 years in the state of North Carolina (NC). (From Reference 11, with permission.)

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    Fig. 4.

    Kaplan-Meier curves by ProVent Score for a multicenter cohort of chronic critical illness patients. The cumulative ProVent score is calculated based upon presence of risk factors on day 21 of mechanical ventilation: age ≥ 65 years – 2 points; age 50–64 years – 1 point; platelets ≤ 150 × 109/L – 1 point; vasopressors – 1 point; hemodialysis – 1 point. (From Reference 46, with permission.)

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    Fig. 5.

    Number of limitations in activities of daily living for chronic critical illness patients. The white bars represent patients ventilated for ≥ 96 hours with a tracheostomy. The black bars represent patients ventilated for ≥ 21 days. (From Reference 41, with permission.)

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    Fig. 6.

    Trajectories of care over the first year after discharge for a cohort of patients requiring prolonged mechanical ventilation in a United States tertiary care hospital. Arrows between locations indicate both the direction of patient transitions and the total number of patients transferred between locations over one year. Solid lines represent initial transitions between the hospital and other locations. Dashed lines represent subsequent hospital readmissions and discharges involving post-discharge care locations. Dotted lines represent transitions among post-discharge care locations, including home. Each box summarizes the total numbers of both readmissions and patients admitted, as well as how many patients remained or died in each location of care at one year. * Seven transitions to in-patient hospice and death not shown (3 from the acute hospitalization and 1 each from home, long-term acute care facility, skilled nursing facility, and hospital readmission). One transition from skilled nursing facility to skilled nursing facility not shown. (From Reference 48, with permission.)

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    Fig. 7.

    Projected annual hospitalization days in 10-year increments spent by patients on prolonged acute mechanical ventilation in various strata of hospital care. (From Reference 29, with permission.)

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Respiratory Care: 57 (6)
Respiratory Care
Vol. 57, Issue 6
1 Jun 2012
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Definitions and Epidemiology of the Chronically Critically Ill
Shannon S Carson
Respiratory Care Jun 2012, 57 (6) 848-858; DOI: 10.4187/respcare.01736

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Definitions and Epidemiology of the Chronically Critically Ill
Shannon S Carson
Respiratory Care Jun 2012, 57 (6) 848-858; DOI: 10.4187/respcare.01736
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Keywords

  • chronic critical illness
  • ICU
  • tracheostomy
  • mechanical ventilation.

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