Skip to main content
 

Main menu

  • Home
  • Content
    • Current Issue
    • Editor's Commentary
    • Archives
    • Most-Read Papers of 2022
  • Authors
    • Author Guidelines
    • Submit a Manuscript
  • Reviewers
    • Reviewer Information
    • Create Reviewer Account
    • Reviewer Guidelines: Original Research
    • Reviewer Guidelines: Reviews
    • Appreciation of Reviewers
  • CRCE
    • Through the Journal
    • JournalCasts
    • AARC University
    • PowerPoint Template
  • Open Forum
    • 2023 Call for Abstracts
    • 2022 Abstracts
    • Previous Open Forums
  • Podcast
    • English
    • Español
    • Portugûes
    • 国语
  • Videos
    • Video Abstracts
    • Author Interviews
    • Highlighted Articles
    • The Journal

User menu

  • Subscribe
  • My alerts
  • Log in

Search

  • Advanced search
American Association for Respiratory Care
  • Subscribe
  • My alerts
  • Log in
American Association for Respiratory Care

Advanced Search

  • Home
  • Content
    • Current Issue
    • Editor's Commentary
    • Archives
    • Most-Read Papers of 2022
  • Authors
    • Author Guidelines
    • Submit a Manuscript
  • Reviewers
    • Reviewer Information
    • Create Reviewer Account
    • Reviewer Guidelines: Original Research
    • Reviewer Guidelines: Reviews
    • Appreciation of Reviewers
  • CRCE
    • Through the Journal
    • JournalCasts
    • AARC University
    • PowerPoint Template
  • Open Forum
    • 2023 Call for Abstracts
    • 2022 Abstracts
    • Previous Open Forums
  • Podcast
    • English
    • Español
    • Portugûes
    • 国语
  • Videos
    • Video Abstracts
    • Author Interviews
    • Highlighted Articles
    • The Journal
  • Twitter
  • Facebook
  • YouTube
Research ArticleOriginal Research

Implementation of an Inhaled Nitric Oxide Protocol Decreases Direct Cost Associated With Its Use

Deanna R Todd Tzanetos, Jon J Housley, Frederick E Barr, Warren L May and Cheri D Landers
Respiratory Care May 2015, 60 (5) 644-650; DOI: https://doi.org/10.4187/respcare.03308
Deanna R Todd Tzanetos
Department of Pediatrics, Division of Critical Care, University of Louisville School of Medicine, Louisville, Kentucky.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Jon J Housley
Hospital Administration, UK HealthCare, Lexington, Kentucky.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Frederick E Barr
Department of Pediatrics, Division of Critical Care
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Warren L May
Department of Medicine and Center of Biostatistics/Bioinformatics, University of Mississippi, Jackson, Mississippi.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cheri D Landers
Department of Pediatrics, Division of Critical Care, University of Kentucky School of Medicine, Lexington, Kentucky.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

Abstract

BACKGROUND: The objective of this study was to determine whether the implementation of an inhaled nitric oxide protocol (INO) in a pediatric ICU (PICU) would reduce cost associated with its use without negatively affecting patient outcomes.

METHODS: This is a retrospective cohort study of 76 subjects who required INO therapy in the PICU during the study period. A nitric oxide setup and weaning protocol was implemented in the PICU. The medical records of subjects who had received INO 18 months after protocol implementation, as well as the medical records of subjects who had received INO in the 18 months before protocol implementation, were reviewed. Length of time on INO, cost of INO per subject, mortality, stay, and ventilator hours were recorded.

RESULTS: There were 38 subjects in the pre-protocol group and 38 subjects in the post-protocol group. There was a statistically significant decrease in the median per subject cost of INO between the pre- and post-protocol groups (P < .01). There was no statistically significant difference in the median duration of INO use (P = .06), median PICU (P = .42) or hospital (P = .58) stay, median duration of mechanical ventilation (P = .79) or percent mortality (P = .28) between the 2 groups.

CONCLUSIONS: Implementation of an INO setup and weaning protocol in a PICU reduces the cost associated with its use without a statistically significant difference in mortality. In an era of increased awareness regarding healthcare spending, implementation of evidence-based protocols can provide a way to ensure the judicious utilization of medical resources.

  • pediatrics
  • pulmonary hypertension
  • protocols/practice guidelines

Footnotes

  • Correspondence: Deanna Todd Tzanetos MD MSCI, Department of Pediatrics, Division of Critical Care, University of Louisville School of Medicine, 571 S Floyd Street, Suite 332, Louisville, KY 40202. E-mail: drtzan01{at}louisville.edu.
  • Dr Barr discloses a relationship with Asklepion Pharmaceuticals; all other authors report no conflicts of interest.

  • See the Related Editorial on Page 760

  • Copyright © 2015 by Daedalus Enterprises
View Full Text
PreviousNext
Back to top

In this issue

Respiratory Care: 60 (5)
Respiratory Care
Vol. 60, Issue 5
1 May 2015
  • Table of Contents
  • Table of Contents (PDF)
  • Cover (PDF)
  • Index by author

 

Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Association for Respiratory Care.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Implementation of an Inhaled Nitric Oxide Protocol Decreases Direct Cost Associated With Its Use
(Your Name) has sent you a message from American Association for Respiratory Care
(Your Name) thought you would like to see the American Association for Respiratory Care web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Implementation of an Inhaled Nitric Oxide Protocol Decreases Direct Cost Associated With Its Use
Deanna R Todd Tzanetos, Jon J Housley, Frederick E Barr, Warren L May, Cheri D Landers
Respiratory Care May 2015, 60 (5) 644-650; DOI: 10.4187/respcare.03308

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Implementation of an Inhaled Nitric Oxide Protocol Decreases Direct Cost Associated With Its Use
Deanna R Todd Tzanetos, Jon J Housley, Frederick E Barr, Warren L May, Cheri D Landers
Respiratory Care May 2015, 60 (5) 644-650; DOI: 10.4187/respcare.03308
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

Cited By...

Keywords

  • pediatrics
  • pulmonary hypertension
  • protocols/practice guidelines

Info For

  • Subscribers
  • Institutions
  • Advertisers

About Us

  • About the Journal
  • Editorial Board

AARC

  • Membership
  • Meetings
  • Clinical Practice Guidelines

More

  • Contact Us
  • RSS
American Association for Respiratory Care

Print ISSN: 0020-1324        Online ISSN: 1943-3654

© Daedalus Enterprises, Inc.

Powered by HighWire