Skip to main content
 

Main menu

  • Home
  • Content
    • Current Issue
    • Editor's Commentary
    • Archives
    • Most-Read Papers of 2022
  • Authors
    • Author Guidelines
    • Submit a Manuscript
  • Reviewers
    • Reviewer Information
    • Create Reviewer Account
    • Reviewer Guidelines: Original Research
    • Reviewer Guidelines: Reviews
    • Appreciation of Reviewers
  • CRCE
    • Through the Journal
    • JournalCasts
    • AARC University
    • PowerPoint Template
  • Open Forum
    • 2023 Open Forum
    • 2023 Abstracts
    • Previous Open Forums
  • Podcast
    • English
    • Español
    • Portugûes
    • 国语
  • Videos
    • Video Abstracts
    • Author Interviews
    • The Journal

User menu

  • Subscribe
  • My alerts
  • Log in

Search

  • Advanced search
American Association for Respiratory Care
  • Subscribe
  • My alerts
  • Log in
American Association for Respiratory Care

Advanced Search

  • Home
  • Content
    • Current Issue
    • Editor's Commentary
    • Archives
    • Most-Read Papers of 2022
  • Authors
    • Author Guidelines
    • Submit a Manuscript
  • Reviewers
    • Reviewer Information
    • Create Reviewer Account
    • Reviewer Guidelines: Original Research
    • Reviewer Guidelines: Reviews
    • Appreciation of Reviewers
  • CRCE
    • Through the Journal
    • JournalCasts
    • AARC University
    • PowerPoint Template
  • Open Forum
    • 2023 Open Forum
    • 2023 Abstracts
    • Previous Open Forums
  • Podcast
    • English
    • Español
    • Portugûes
    • 国语
  • Videos
    • Video Abstracts
    • Author Interviews
    • The Journal
  • Twitter
  • Facebook
  • YouTube
Research ArticleConference Proceedings

Aerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula

Dean R Hess
Respiratory Care June 2015, 60 (6) 880-893; DOI: https://doi.org/10.4187/respcare.04042
Dean R Hess
Respiratory Care Department, Massachusetts General Hospital, and the Department of Anesthesia, Harvard Medical School, Boston, Massachusetts.
PhD RRT FAARC
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
  • Article
  • Figures & Data
  • Info & Metrics
  • References
  • PDF
Loading

Abstract

Noninvasive ventilation (NIV) and high-flow nasal cannula (HFNC) are increasingly used for patients with acute respiratory failure. Some patients receiving these therapies might also benefit from inhaled drug delivery. Thus, it is attractive to combine aerosol therapy with NIV or HFNC. The purpose of this paper is to review the available evidence related to the use of inhaled aerosols with NIV or HFNC. Available evidence supports the delivery of aerosols during NIV. Inhaled bronchodilator response might be improved with the use of NIV in acute asthma, but the evidence is not sufficiently mature to recommend this as standard therapy. Evidence does support aerosol delivery without discontinuation of NIV. Clinical studies on aerosol delivery during HFNC are needed, and based on the available in vitro evidence, it is not possible to make a recommendation for or against aerosol delivery during HFNC.

  • aerosol
  • high-flow nasal cannula
  • inhaler
  • nebulizer
  • noninvasive ventilation

Footnotes

  • Correspondence: Dean R Hess PhD RRT FAARC, Respiratory Care Department, Ellison 401, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114. E-mail: dhess{at}mgh.harvard.edu.
  • Dr Hess discloses relationships with Philips Respironics, PARI, Bayer, Merck, UpToDate, McGraw-Hill, Jones & Bartlett Learning, and the American Board of Internal Medicine.

  • Dr Hess presented a version of this paper at the 53rd Respiratory Care Journal Conference on Aerosol Drug Delivery in Respiratory Care, held June 6–7, 2014, in St Petersburg, Florida.

  • ↵* Neil R MacIntyre MD FAARC, Division of Pulmonary and Critical Care Medicine, Duke University, Durham, North Carolina, representing InspiRx.

  • ↵† James B Fink PhD RRT FAARC, James B Fink LLC, San Mateo, California, and Division of Respiratory Therapy, Georgia State University, Atlanta, Georgia, representing Aerogen.

  • Copyright © 2015 by Daedalus Enterprises
View Full Text
PreviousNext
Back to top

In this issue

Respiratory Care: 60 (6)
Respiratory Care
Vol. 60, Issue 6
1 Jun 2015
  • Table of Contents
  • Table of Contents (PDF)
  • Cover (PDF)
  • Index by author
  • Monthly Podcast

 

Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on American Association for Respiratory Care.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Aerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula
(Your Name) has sent you a message from American Association for Respiratory Care
(Your Name) thought you would like to see the American Association for Respiratory Care web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Aerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula
Dean R Hess
Respiratory Care Jun 2015, 60 (6) 880-893; DOI: 10.4187/respcare.04042

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Aerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula
Dean R Hess
Respiratory Care Jun 2015, 60 (6) 880-893; DOI: 10.4187/respcare.04042
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Aerosol Therapy During NIV
    • Aerosol Delivery During HFNC
    • Conclusions
    • Discussion
    • Footnotes
    • References
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

Cited By...

Keywords

  • aerosol
  • high-flow nasal cannula
  • inhaler
  • nebulizer
  • noninvasive ventilation

Info For

  • Subscribers
  • Institutions
  • Advertisers

About Us

  • About the Journal
  • Editorial Board

AARC

  • Membership
  • Meetings
  • Clinical Practice Guidelines

More

  • Contact Us
  • RSS
American Association for Respiratory Care

Print ISSN: 0020-1324        Online ISSN: 1943-3654

© Daedalus Enterprises, Inc.

Powered by HighWire