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Research ArticleConference Proceedings

Aerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula

Dean R Hess
Respiratory Care June 2015, 60 (6) 880-893; DOI: https://doi.org/10.4187/respcare.04042
Dean R Hess
Respiratory Care Department, Massachusetts General Hospital, and the Department of Anesthesia, Harvard Medical School, Boston, Massachusetts.
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References

  1. 1.↵
    1. Hess DR
    . Noninvasive ventilation for acute respiratory failure. Respir Care 2013;58(6):950-972.
    OpenUrlAbstract/FREE Full Text
  2. 2.↵
    1. Cabrini L,
    2. Landoni G,
    3. Oriani A,
    4. Plumari VP,
    5. Nobile L,
    6. Greco M,
    7. et al
    . Noninvasive ventilation and survival in acute care settings: a comprehensive systematic review and meta-analysis of randomized controlled trials. Crit Care Med 2015;43(4):880-888.
    OpenUrlPubMed
  3. 3.↵
    1. Soroksky A,
    2. Klinowski E,
    3. Ilgyev E,
    4. Mizrachi A,
    5. Miller A,
    6. Ben Yehuda TM,
    7. et al
    . Noninvasive positive pressure ventilation in acute asthmatic attack. Eur Respir Rev 2010;19(115):39-45.
    OpenUrlAbstract/FREE Full Text
  4. 4.↵
    1. Nanchal R,
    2. Kumar G,
    3. Majumdar T,
    4. Taneja A,
    5. Patel J,
    6. Dagar G,
    7. et al
    . Utilization of mechanical ventilation for asthma exacerbations: analysis of a national database. Respir Care 2014;59(5):644-653.
    OpenUrlAbstract/FREE Full Text
  5. 5.↵
    1. Carteaux G,
    2. Lyazidi A,
    3. Cordoba-Izquierdo A,
    4. Vignaux L,
    5. Jolliet P,
    6. Thille AW,
    7. et al
    . Patient-ventilator asynchrony during noninvasive ventilation: a bench and clinical study. Chest 2012;142(2):367-376.
    OpenUrlCrossRefPubMed
  6. 6.↵
    1. Ceriana P,
    2. Navalesi P,
    3. Rampulla C,
    4. Prinianakis G,
    5. Nava S
    . Use of bronchodilators during non-invasive mechanical ventilation. Monaldi Arch Chest Dis 2003;59(2):123-127.
    OpenUrlPubMed
  7. 7.↵
    1. Dhand R
    . Aerosol therapy in patients receiving noninvasive positive pressure ventilation. J Aerosol Med Pulm Drug Deliv 2012;25(2):63-78.
    OpenUrlPubMed
  8. 8.↵
    1. Hess DR
    . The mask for noninvasive ventilation: principles of design and effects on aerosol delivery. J Aerosol Med 2007;20(Suppl 1):S85-S98; discussion S98-S89.
    OpenUrlCrossRefPubMedWeb of Science
  9. 9.↵
    1. Chatmongkolchart S,
    2. Schettino GP,
    3. Dillman C,
    4. Kacmarek RM,
    5. Hess DR
    . In vitro evaluation of aerosol bronchodilator delivery during noninvasive positive pressure ventilation: effect of ventilator settings and nebulizer position. Crit Care Med 2002;30(11):2515-2519.
    OpenUrlCrossRefPubMedWeb of Science
  10. 10.↵
    1. Branconnier MP,
    2. Hess DR
    . Albuterol delivery during noninvasive ventilation. Respir Care 2005;50(12):1649-1653.
    OpenUrlAbstract/FREE Full Text
  11. 11.↵
    1. Calvert LD,
    2. Jackson JM,
    3. White JA,
    4. Barry PW,
    5. Kinnear WJ,
    6. O'Callaghan C
    . Enhanced delivery of nebulised salbutamol during non-invasive ventilation. J Pharm Pharmacol 2006;58(11):1553-1557.
    OpenUrlPubMedWeb of Science
  12. 12.↵
    1. Abdelrahim ME,
    2. Plant P,
    3. Chrystyn H
    . In-vitro characterisation of the nebulised dose during non-invasive ventilation. J Pharm Pharmacol 2010;62(8):966-972.
    OpenUrlPubMed
  13. 13.↵
    1. White CC,
    2. Crotwell DN,
    3. Shen S,
    4. Salyer J,
    5. Yung D,
    6. Zheng J,
    7. DiBlasi RM
    . Bronchodilator delivery during simulated pediatric noninvasive ventilation. Respir Care 2013;58(9):1459-1466.
    OpenUrlAbstract/FREE Full Text
  14. 14.↵
    1. Michotte JB,
    2. Jossen E,
    3. Roeseler J,
    4. Liistro G,
    5. Reychler G
    . In vitro comparison of five nebulizers during noninvasive ventilation: analysis of inhaled and lost doses. J Aerosol Med Pulm Drug Deliv 2014;27(6):430-440.
    OpenUrlPubMed
  15. 15.↵
    1. Dai B,
    2. Kang J,
    3. Sun LF,
    4. Tan W,
    5. Zhao HW
    . Influence of exhalation valve and nebulizer position on albuterol delivery during noninvasive positive pressure ventilation. J Aerosol Med Pulm Drug Deliv 2014;27(2):125-132.
    OpenUrlPubMed
  16. 16.↵
    1. Reychler G,
    2. Leal T,
    3. Roeseler J,
    4. Thys F,
    5. Delvau N,
    6. Liistro G
    . Effect of continuous positive airway pressure combined to nebulization on lung deposition measured by urinary excretion of amikacin. Respir Med 2007;101(10):2051-2055.
    OpenUrlPubMed
  17. 17.↵
    1. França EE,
    2. Dornelas de Andrade AF,
    3. Cabral G,
    4. Almeida Filho P,
    5. Silva KC,
    6. Galindo Filho VC,
    7. et al
    . Nebulization associated with bi-level noninvasive ventilation: analysis of pulmonary radioaerosol deposition. Respir Med 2006;100(4):721-728.
    OpenUrlCrossRefPubMedWeb of Science
  18. 18.↵
    1. Maccari JG,
    2. Teixeira C,
    3. Savi A,
    4. de Oliveira RP,
    5. Machado AS,
    6. Tonietto TF,
    7. et al
    . Nebulization during spontaneous breathing, CPAP, and bi-level positive-pressure ventilation: a randomized analysis of pulmonary radioaerosol deposition. Respir Care 2014;59(4):479-484.
    OpenUrlAbstract/FREE Full Text
  19. 19.↵
    1. Parkes SN,
    2. Bersten AD
    . Aerosol kinetics and bronchodilator efficacy during continuous positive airway pressure delivered by face mask. Thorax 1997;52(2):171-175.
    OpenUrlAbstract
  20. 20.↵
    1. Pollack CV Jr.,
    2. Fleisch KB,
    3. Dowsey K
    . Treatment of acute bronchospasm with beta-adrenergic agonist aerosols delivered by a nasal bilevel positive airway pressure circuit. Ann Emerg Med 1995;26(5):552-557.
    OpenUrlCrossRefPubMedWeb of Science
  21. 21.↵
    1. Brandão DC,
    2. Lima VM,
    3. Filho VG,
    4. Silva TS,
    5. Campos TF,
    6. Dean E,
    7. de Andrade AD
    . Reversal of bronchial obstruction with bi-level positive airway pressure and nebulization in patients with acute asthma. J Asthma 2009;46(4):356-361.
    OpenUrlCrossRefPubMed
  22. 22.↵
    1. Galindo-Filho VC,
    2. Brandão DC,
    3. Ferreira Rde C,
    4. Menezes MJ,
    5. Almeida-Filho P,
    6. Parreira VF,
    7. et al
    . Noninvasive ventilation coupled with nebulization during asthma crises: a randomized controlled trial. Respir Care 2013;58(2):241-249.
    OpenUrlAbstract/FREE Full Text
  23. 23.↵
    1. Soroksky A,
    2. Stav D,
    3. Shpirer I
    . A pilot prospective, randomized, placebo-controlled trial of bilevel positive airway pressure in acute asthmatic attack. Chest 2003;123(4):1018-1025.
    OpenUrlCrossRefPubMedWeb of Science
  24. 24.↵
    1. Soma T,
    2. Hino M,
    3. Kida K,
    4. Kudoh S
    . A prospective and randomized study for improvement of acute asthma by non-invasive positive pressure ventilation (NPPV). Intern Med 2008;47(6):493-501.
    OpenUrlCrossRefPubMed
  25. 25.↵
    1. Gupta D,
    2. Nath A,
    3. Agarwal R,
    4. Behera D
    . A prospective randomized controlled trial on the efficacy of noninvasive ventilation in severe acute asthma. Respir Care 2010;55(5):536-543.
    OpenUrlAbstract/FREE Full Text
  26. 26.↵
    1. Mukhopadhyay A,
    2. Dela Pena E,
    3. Wadden B,
    4. Procyshyn M,
    5. Keang Lim T
    . Effects of inhalational bronchodilator treatment during noninvasive ventilation in severe chronic obstructive pulmonary disease exacerbations. J Crit Care 2009;24(3):474.e1-474.e5.
    OpenUrlPubMed
  27. 27.↵
    1. Nava S,
    2. Karakurt S,
    3. Rampulla C,
    4. Braschi A,
    5. Fanfulla F
    . Salbutamol delivery during non-invasive mechanical ventilation in patients with chronic obstructive pulmonary disease: a randomized, controlled study. Intensive Care Med 2001;27(10):1627-1635.
    OpenUrlCrossRefPubMedWeb of Science
  28. 28.↵
    1. Fauroux B,
    2. Itti E,
    3. Pigeot J,
    4. Isabey D,
    5. Meignan M,
    6. Ferry G,
    7. et al
    . Optimization of aerosol deposition by pressure support in children with cystic fibrosis: an experimental and clinical study. Am J Respir Crit Care Med 2000;162(6):2265-2271.
    OpenUrlPubMed
  29. 29.↵
    1. Iosson N
    . Images in clinical medicine. Nebulizer-associated anisocoria. N Engl J Med 2006;354(9):e8.
    OpenUrlCrossRefPubMedWeb of Science
  30. 30.↵
    1. Bhashyam AR,
    2. Wolf MT,
    3. Marcinkowski AL,
    4. Saville A,
    5. Thomas K,
    6. Carcillo JA,
    7. Corcoran TE
    . Aerosol delivery through nasal cannulas: an in vitro study. J Aerosol Med Pulm Drug Deliv 2008;21(2):181-188.
    OpenUrlPubMed
  31. 31.↵
    1. Ari A,
    2. Harwood R,
    3. Sheard M,
    4. Dailey P,
    5. Fink JB
    . In vitro comparison of heliox and oxygen in aerosol delivery using pediatric high flow nasal cannula. Pediatr Pulmonol 2011;46(8):795-801.
    OpenUrlCrossRefPubMed
  32. 32.↵
    1. Perry SA,
    2. Kesser KC,
    3. Geller DE,
    4. Selhorst DM,
    5. Rendle JK,
    6. Hertzog JH
    . Influences of cannula size and flow rate on aerosol drug delivery through the Vapotherm humidified high-flow nasal cannula system. Pediatr Crit Care Med 2013;14(5):e250–e256.
    OpenUrlPubMed
  33. 33.↵
    1. Hindle M,
    2. Longest PW
    . Evaluation of enhanced condensational growth (ECG) for controlled respiratory drug delivery in a mouth-throat and upper tracheobronchial model. Pharm Res 2010;27(9):1800-1811.
    OpenUrlPubMed
  34. 34.
    1. Longest PW,
    2. Hindle M
    . CFD simulations of enhanced condensational growth (ECG) applied to respiratory drug delivery with comparisons to in vitro data. J Aerosol Sci 2010;41(8):805-820.
    OpenUrlPubMed
  35. 35.
    1. Longest PW,
    2. McLeskey JT Jr.,
    3. Hindle M
    . Characterization of nanoaerosol size change during enhanced condensational growth. Aerosol Sci Technol 2010;44(6):473-483.
    OpenUrlPubMed
  36. 36.
    1. Longest PW,
    2. Tian G,
    3. Hindle M
    . Improving the lung delivery of nasally administered aerosols during noninvasive ventilation–an application of enhanced condensational growth (ECG). J Aerosol Med Pulm Drug Deliv 2011;24(2):103-118.
    OpenUrlPubMed
  37. 37.
    1. Tian G,
    2. Longest PW,
    3. Su G,
    4. Hindle M
    . Characterization of respiratory drug delivery with enhanced condensational growth using an individual path model of the entire tracheobronchial airways. Ann Biomed Eng 2011;39(3):1136-1153.
    OpenUrlPubMed
  38. 38.
    1. Hindle M,
    2. Longest PW
    . Condensational growth of combination drug-excipient submicrometer particles for targeted high-efficiency pulmonary delivery: evaluation of formulation and delivery device. J Pharm Pharmacol 2012;64(9):1254-1263.
    OpenUrlPubMed
  39. 39.
    1. Longest PW,
    2. Hindle M
    . Condensational growth of combination drug-excipient submicrometer particles for targeted high efficiency pulmonary delivery: comparison of CFD predictions with experimental results. Pharm Res 2012;29(3):707-721.
    OpenUrlPubMed
  40. 40.
    1. Longest PW,
    2. Spence BM,
    3. Holbrook LT,
    4. Mossi KM,
    5. Son YJ,
    6. Hindle M
    . Production of inhalable submicrometer aerosols from conventional mesh nebulizers for improved respiratory drug delivery. J Aerosol Sci 2012;51:66-80.
    OpenUrlPubMed
  41. 41.
    1. Longest PW,
    2. Tian G,
    3. Li X,
    4. Son YJ,
    5. Hindle M
    . Performance of combination drug and hygroscopic excipient submicrometer particles from a softmist inhaler in a characteristic model of the airways. Ann Biomed Eng 2012;40(12):2596-2610.
    OpenUrlPubMed
  42. 42.
    1. Golshahi L,
    2. Tian G,
    3. Azimi M,
    4. Son YJ,
    5. Walenga R,
    6. Longest PW,
    7. Hindle M
    . The use of condensational growth methods for efficient drug delivery to the lungs during noninvasive ventilation high flow therapy. Pharm Res 2013;30(11):2917-2930.
    OpenUrlPubMed
  43. 43.↵
    1. Longest PW,
    2. Walenga RL,
    3. Son YJ,
    4. Hindle M
    . High-efficiency generation and delivery of aerosols through nasal cannula during noninvasive ventilation. J Aerosol Med Pulm Drug Deliv 2013;26(5):266-279.
    OpenUrlPubMed
  44. 44.
    1. Tian G,
    2. Longest PW,
    3. Li X,
    4. Hindle M
    . Targeting aerosol deposition to and within the lung airways using excipient enhanced growth. J Aerosol Med Pulm Drug Deliv 2013;26(5):248-265.
    OpenUrlPubMed
  45. 45.↵
    1. Golshahi L,
    2. Longest PW,
    3. Azimi M,
    4. Syed A,
    5. Hindle M
    . Intermittent aerosol delivery to the lungs during high-flow nasal cannula therapy. Respir Care 2014;59(10):1476-1486.
    OpenUrlAbstract/FREE Full Text
  46. 46.↵
    1. Longest PW,
    2. Tian G
    . Development of a new technique for the efficient delivery of aerosolized medications to infants on mechanical ventilation. Pharm Res 2015;32(1):321-336.
    OpenUrlPubMed
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Respiratory Care: 60 (6)
Respiratory Care
Vol. 60, Issue 6
1 Jun 2015
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Aerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula
Dean R Hess
Respiratory Care Jun 2015, 60 (6) 880-893; DOI: 10.4187/respcare.04042

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Aerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula
Dean R Hess
Respiratory Care Jun 2015, 60 (6) 880-893; DOI: 10.4187/respcare.04042
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Keywords

  • aerosol
  • high-flow nasal cannula
  • inhaler
  • nebulizer
  • noninvasive ventilation

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