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Review ArticleInvited Review

High-Flow Nasal Cannula Oxygen Therapy in Adults: Physiological Benefits, Indication, Clinical Benefits, and Adverse Effects

Masaji Nishimura
Respiratory Care April 2016, 61 (4) 529-541; DOI: https://doi.org/10.4187/respcare.04577
Masaji Nishimura
Department of Emergency and Critical Care Medicine, Tokushima University Graduate School, Kuramoto, Tokushima, Japan.
MD PhD
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Article Information

vol. 61 no. 4 529-541
DOI 
https://doi.org/10.4187/respcare.04577
PubMed 
27016353

Published By 
Respiratory Care
Print ISSN 
0020-1324
Online ISSN 
1943-3654
History 
  • Published online March 25, 2016.

Copyright & Usage 
Copyright © 2016 by Daedalus Enterprises

Author Information

  1. Masaji Nishimura, MD PhD⇑
  1. Department of Emergency and Critical Care Medicine, Tokushima University Graduate School, Kuramoto, Tokushima, Japan.
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Respiratory Care: 61 (4)
Respiratory Care
Vol. 61, Issue 4
1 Apr 2016
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High-Flow Nasal Cannula Oxygen Therapy in Adults: Physiological Benefits, Indication, Clinical Benefits, and Adverse Effects
Masaji Nishimura
Respiratory Care Apr 2016, 61 (4) 529-541; DOI: 10.4187/respcare.04577

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High-Flow Nasal Cannula Oxygen Therapy in Adults: Physiological Benefits, Indication, Clinical Benefits, and Adverse Effects
Masaji Nishimura
Respiratory Care Apr 2016, 61 (4) 529-541; DOI: 10.4187/respcare.04577
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  • Article
    • Abstract
    • Introduction
    • Adverse Effects of Lack of Humidification
    • Humidification Performance of HFNC Devices
    • Interface
    • Physiological Effect
    • Fraction of Inspired Oxygen
    • PEEP Effect
    • Clinical Trials
    • Hypercapnic Respiratory Failure
    • Hypoxemic Respiratory Failure
    • Postextubation
    • Preintubation Oxygenation
    • Acute Heart Failure
    • Sleep Apnea
    • Other Conditions
    • Adverse Effects
    • Contraindication
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
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  • References
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Keywords

  • noninvasive ventilation
  • high-flow oxygen therapy
  • escalation
  • randomized
  • controlled trials
  • humidification

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