Article Figures & Data
Figures
- Fig. 1.
Effect of albuterol on minimal inspiratory resistance in 12 stable mechanically ventilated subjects with COPD. Significant decreases in minimal inspiratory resistance occurred within 5 min of administration of 4 puffs of albuterol. The addition of 8 and 16 puffs (cumulative doses of 12 and 28 puffs, respectively) did not achieve a significantly greater effect than that with 4 puffs (P > .05). Bars represent SE. *P < .001. From Reference 17, with permission.
- Fig. 2.
Effect of albuterol on maximum inspiratory airway resistance (Rmax) in stable, mechanically ventilated subjects with COPD. There was a decrease in airway resistance from baseline values within 10 min of albuterol administration. A: Change in airway resistance from baseline (time 0) after 4 doses of albuterol from a pressurized metered-dose inhalers (pMDI). B: Change in airway resistance from baseline (time 0) after 2.5 mg of albuterol given by nebulizer. Significant reductions in airway resistance were sustained for 2 h and returned to baseline by 4 h. The response to albuterol administered by pMDI (0.4 mg) was comparable to that achieved with 2.5 mg administered by nebulizer. Bars represent SEM. *P < .01. **P < .05. From Reference 18.
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- Introduction
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- Choice of Aerosol Delivery Device in Mechanically Ventilated Patients
- Drugs Administered via Inhalation to Mechanically Ventilated Patients
- Goal-Directed Aerosol Therapy in Mechanically Ventilated Patients
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