Assessment of Bohr and Enghoff Dead Space Equations in Mechanically Ventilated Children

References

1. 1.↵
   1. Bohr C

   . Ueber die Lungenathmung1. Skand Arch Für Physiol. 1891;2(1):236–268.

   OpenUrl
2. 2.↵
   1. McSwain SD,
   2. Hamel DS,
   3. Smith PB,
   4. Gentile MA,
   5. Srinivasan S,
   6. Meliones JN,
   7. Cheifetz IM

   . end-tidal and arterial carbon dioxide measurements correlate across levels of physiologic dead space. Respir Care 2010;55(3):288–293.

   OpenUrlAbstract/FREE Full Text
3. 3.↵
   1. Charron C,
   2. Repesse X,
   3. Bouferrache K,
   4. Bodson L,
   5. Castro S,
   6. Page B,
   7. et al

   . PaCO2 and alveolar dead space are more relevant than PaO2/FiO2 ratio in monitoring the respiratory response to prone position in ARDS Subjects: a physiological study. Crit Care 2011;15(4):R175.

   OpenUrlPubMed
4. 4.↵
   1. Wenzel U,
   2. Rüdiger M,
   3. Wagner MH,
   4. Waeur RR

   . Utility of deadspace and capnometry measurements in determination of surfactant efficacy in surfactant-depleted lungs. Crit Care Med 1999;27(5):946–952.

   OpenUrlCrossRefPubMedWeb of Science
5. 5.↵
   1. Maisch S,
   2. Reissmann H,
   3. Fuellekrug B,
   4. Weismann D,
   5. Rutkowski T,
   6. Tusman G,
   7. Bohm SH

   . Compliance and dead space fraction indicate an optimal level of end-expiratory pressure after recruitement in anesthetized pateints. Anesth Analg 2008;106(1):175–181, table of contents.

   OpenUrlCrossRefPubMedWeb of Science
6. 6.↵
   1. Tusman G,
   2. Suarez-Sipmann F,
   3. Böhm SH,
   4. Pech T,
   5. Reissmann H,
   6. Meschino G,
   7. et al

   . Monitoring dead space during recruitment and PEEP titration in an experimental model. Intensive Care Med 2006;32(11):1863–1871.

   OpenUrlCrossRefPubMedWeb of Science
7. 7.↵
   1. Nuckton TJ,
   2. Alonso JA,
   3. Kallet RH,
   4. Daniel BM,
   5. Pittet JF,
   6. Eisner MD,
   7. Matthay MA

   . Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med 2002;346(17):1281–1286.

   OpenUrlCrossRefPubMedWeb of Science
8. 8.↵
   1. Almeida-Junior AA,
   2. da Silva MT,
   3. Almeida CC,
   4. Ribeiro JD

   . Relationship between physiologic deadspace/tidal volume ratio and gas exchange in infants with acute bronchiolitis on invasive mechanical ventilation. Pediatr Crit Care Med 2007;8(4):372–377.

   OpenUrlPubMed
9. 9.↵
   1. Tusman G,
   2. Sipmann FS,
   3. Borges JB,
   4. Hedenstierna G,
   5. Bohm SH

   . Validation of Bohr dead space measured by volumetric capnography. Intensive Care Med 2011;37(5):870–874.

   OpenUrlCrossRefPubMedWeb of Science
10. 10.↵
    1. Tusman G,
    2. Sipmann FS,
    3. Bohm SH

    . Rationale of dead space measurement by volumetric capnography. Anesth Analg 2012;114(4):866–874.

    OpenUrlCrossRefPubMedWeb of Science
11. 11.↵
    1. Ranieri VM,
    2. Rubenfeld GD,
    3. Thompson BT,
    4. Ferguson ND,
    5. Caldwell E,
    6. et al

    ARDS Definition Task Force Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, et al. The Berlin definition of acute respiratory distress syndrome. JAMA 2012;307(23):2526–2533.

    OpenUrlCrossRefPubMedWeb of Science
12. 12.↵
    1. Wagner PD

    . Causes of a high physiological dead space in critically ill subjects. Crit Care 2008;12(3):148.

    OpenUrlCrossRefPubMed
13. 13.↵
    1. Hedenstierna G,
    2. Sandhagen B

    . Assessing deadspace, a meaningful variable? Minerva Anestesiol 2006;72(6):521–528.

    OpenUrlPubMedWeb of Science
14. 14.↵
    1. Suarez-Sipmann F,
    2. Santos A,
    3. Böhm SH,
    4. Borges JB,
    5. Hedenstierna G,
    6. Tusman G

    . Corrections of Enghoff's dead space formula for shunt effects still overestimate Bohr's dead space. Respir Physiol Neurobiol 2013;189(1):99–105.

    OpenUrlCrossRefPubMed
15. 15.↵
    1. Hardman JG,
    2. Aitkenhead AR

    . Estimating alveolar dead space from the arterial to end-tidal CO₂ gradient: a modeling analysis. Anesth Analg 2003;97(6):1846–1851.

    OpenUrlCrossRefPubMedWeb of Science
16. 16.↵
    1. Mecikalski MB,
    2. Cutillo AG,
    3. Renzetti AD

    . Effect of right-to-left shunting on alveolar dead space. Bull Eur Physiopathol Respir 1984;20(6):513–519.

    OpenUrlPubMedWeb of Science
17. 17.↵
    1. Tusman G,
    2. Suarez-Sipmann F,
    3. Bohm SH,
    4. Borges JB,
    5. Hedenstierna G

    . Capnography reflects ventilation/perfusion distribution in a model of acute lung injury: Phase III slope of capnograms is related to the V/Q ratio. Acta Anaesthesiol Scand 2011;55(5):597–606.

    OpenUrlCrossRefPubMedWeb of Science
18. 18.↵
    1. Fuchs SI,
    2. Junge S,
    3. Ellemunter H,
    4. Ballmann M,
    5. Gappa M

    . Calculation of the capnographic index based on expiratory molar mass-volume-curves: a suitable tool to screen for cystic fibrosis lung disease. J Cyst Fibros 2013;12(3):277–283.

    OpenUrl
19. 19.
    1. Fouzas S,
    2. Häcki C,
    3. Latzin P,
    4. Proietti E,
    5. Schulzke S,
    6. Frey U,
    7. Delgado-Eckert E

    . Volumetric capnography in infants with bronchopulmonary dysplasia. J Pediatr 2014;164(2):283–288.e1-3.

    OpenUrl
20. 20.↵
    1. Strömberg NO,
    2. Gustafsson PM

    . Ventilation inhomogeneity assessed by nitrogen washout and ventilation-perfusion mismatch by capnography in stable and induced airway obstruction. Pediatr Pulmonol 2000;29(2):94–102.

    OpenUrlCrossRefPubMedWeb of Science
21. 21.↵
    1. Tusman G,
    2. Suarez-Sipmann F,
    3. Paez G,
    4. Alvarez J,
    5. Bohm SH

    . States of low pulmonary blood flow can be detected non-invasively at the bedside measuring alveolar dead space. J Clin Monit Comput 2012;26(3):183–190.

    OpenUrlPubMed
22. 22.↵
    1. Niklason L,
    2. Eckerström J,
    3. Jonson B

    . The influence of venous admixture on alveolar dead space and carbon dioxide exchange in acute respiratory distress syndrome: computer modelling. Crit Care 2008;12(2):R53.

    OpenUrlCrossRefPubMed
23. 23.↵
    1. Suominen PK,
    2. Stayer S,
    3. Wang W,
    4. Chang AC

    . The effect of temperature correction of blood gas values on the accuracy of end-tidal carbon dioxide monitoring in children after cardiac surgery. ASAIO J 2007;53(6):670–674.

    OpenUrlPubMed
24. 24.↵
    1. Sitzwohl C,
    2. Kettner SC,
    3. Reinprecht A,
    4. Dietrich W,
    5. Klimscha W,
    6. Fridrich P,
    7. et al

    . The arterial to end-tidal carbon dioxide gradient increases with uncorrected but not with temperature-corrected PaCO2 determination during mild to moderate hypothermia. Anesth Analg 1998;86(5):1131–1136.

    OpenUrlPubMedWeb of Science