Abstract
BACKGROUND: Apnea testing is the last step of brain death assessment. This study aimed to determine whether apnea testing is safer when performed over a shorter duration.
METHODS: The medical records of 200 brain-dead donors were retrospectively evaluated. All the records were anonymously registered in the Japanese Ministry of Health, Labor, and Welfare from 1999 to 2012. The rate of 
increase was analyzed to calculate the duration required for apnea testing.
RESULTS: At baseline, body temperature and 
significantly affected the increase rate of 
. At baseline, the apnea testing durations were 4.7 min with normal body temperature and higher 
(
40–60 mm Hg, body temperature 36.5°C, 
400 mm Hg); further, it was 3.0 min with higher body temperature and lower 
at baseline (
40–60 mm Hg, body temperature 38.0°C, 
100 mm Hg).
CONCLUSIONS: The specific duration of apnea testing during brain death assessment may be predicted by measuring the increase rate of 
.
- apnea
- brain death
- diagnostic tests
- hypoxemia
- hypotension
- organ procurement
- tissue procurement
Footnotes
- Correspondence: Katsuyuki Sagishima MD. E-mail: saggy{at}kuh.kumamoto-u.ac.jp
The authors have disclosed no conflicts of interest.
- Copyright © 2021 by Daedalus Enterprises
Pay Per Article - You may access this article (from the computer you are currently using) for 1 day for US$30.00
Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.
