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Research ArticleFast Track

Clinical Characteristics, Respiratory Mechanics, and Outcomes in Critically Ill Individuals With COVID-19 Infection in an Underserved Urban Population

Siddique Chaudhary, Sadia Benzaquen, Jessica G Woo, Jack Rubinstein, Atul Matta, Jeri Albano, Robert De Joy, Kevin Bryan Lo and Gabriel Patarroyo-Aponte
Respiratory Care June 2021, 66 (6) 897-908; DOI: https://doi.org/10.4187/respcare.08319
Siddique Chaudhary
Division of Pulmonary and Critical Care and Sleep Medicine, Einstein Medical Center, Philadelphia, Pennsylvania.
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  • For correspondence: [email protected]
Sadia Benzaquen
Division of Pulmonary and Critical Care and Sleep Medicine, Einstein Medical Center, Philadelphia, Pennsylvania.
Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania.
Sidney Kimmel College, Thomas Jefferson University, Philadelphia, Pennsylvania.
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Jessica G Woo
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio.
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Jack Rubinstein
Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio.
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Atul Matta
Division of Pulmonary and Critical Care and Sleep Medicine, Einstein Medical Center, Philadelphia, Pennsylvania.
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Jeri Albano
Sidney Kimmel College, Thomas Jefferson University, Philadelphia, Pennsylvania.
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Robert De Joy III
Sidney Kimmel College, Thomas Jefferson University, Philadelphia, Pennsylvania.
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Kevin Bryan Lo
Sidney Kimmel College, Thomas Jefferson University, Philadelphia, Pennsylvania.
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Gabriel Patarroyo-Aponte
Division of Pulmonary and Critical Care and Sleep Medicine, Einstein Medical Center, Philadelphia, Pennsylvania.
Department of Medicine, Einstein Medical Center, Philadelphia, Pennsylvania.
Sidney Kimmel College, Thomas Jefferson University, Philadelphia, Pennsylvania.
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    Fig. 1.

    Longitudinal ventilation parameters associated with in-patient death. Least squares means ± SD presented from mixed models adjusted for race, sex, age, body mass index, and total time on ventilator. (A) Embedded Image ; (B) PEEP; (C) plateau pressure (Pplat); and (D) Embedded Image requirement (%).

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    Fig. 2.

    Longitudinal ventilation parameters not associated with in-patient death. Least squares means ± SD presented from mixed models adjusted for race, sex, age, body mass index, and total time on ventilator. (A) Compliance; (B) mean arterial pressure.

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    Fig. 3.

    Odds ratios (95% CI) of factors associated with in-patient death, by race/ethnicity, presented from race/ethnicity-specific adjusted logistic regression models. The upper limit of the 95% CI for tocilizumab treatment in Black subjects is 180 (not shown). OR = odds ratio.

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Respiratory Care: 66 (6)
Respiratory Care
Vol. 66, Issue 6
1 Jun 2021
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Clinical Characteristics, Respiratory Mechanics, and Outcomes in Critically Ill Individuals With COVID-19 Infection in an Underserved Urban Population
Siddique Chaudhary, Sadia Benzaquen, Jessica G Woo, Jack Rubinstein, Atul Matta, Jeri Albano, Robert De Joy, Kevin Bryan Lo, Gabriel Patarroyo-Aponte
Respiratory Care Jun 2021, 66 (6) 897-908; DOI: 10.4187/respcare.08319

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Clinical Characteristics, Respiratory Mechanics, and Outcomes in Critically Ill Individuals With COVID-19 Infection in an Underserved Urban Population
Siddique Chaudhary, Sadia Benzaquen, Jessica G Woo, Jack Rubinstein, Atul Matta, Jeri Albano, Robert De Joy, Kevin Bryan Lo, Gabriel Patarroyo-Aponte
Respiratory Care Jun 2021, 66 (6) 897-908; DOI: 10.4187/respcare.08319
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