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Research ArticleOriginal Research

Worldwide Clinical Practice of High-Flow Nasal Cannula and Concomitant Aerosol Therapy in the Adult ICU Setting

Jie Li, Meilien Tu, Lei Yang, Guoqiang Jing, James B Fink, Chris Burtin, Armèle Dornelas de Andrade, Lingyue Gong, Lixin Xie and Stephan Ehrmann
Respiratory Care September 2021, 66 (9) 1416-1424; DOI: https://doi.org/10.4187/respcare.08996
Jie Li
Division of Respiratory Care, Department of Cardiopulmonary Sciences, Rush University, Chicago, Illinois.
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  • For correspondence: [email protected] [email protected]
Meilien Tu
Department of Respiratory Care, Chang Gung University of Science and Technology, Taiwan.
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Lei Yang
Hongli Hospital, Xinxiang, Henan, China.
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Guoqiang Jing
Department of Pulmonary and Critical Care Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, China.
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James B Fink
Division of Respiratory Care, Department of Cardiopulmonary Sciences, Rush University, Chicago, Illinois.
Aerogen Pharma Corp, San Mateo, California.
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Chris Burtin
Universiteit Hasselt - Campus Diepenbeek, Hasselt, Belgium.
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Armèle Dornelas de Andrade
Federal University of Pernambuco, Recife, Brazil.
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Lingyue Gong
Division of Respiratory Care, Department of Cardiopulmonary Sciences, Rush University, Chicago, Illinois.
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Lixin Xie
Department of Respiratory and Critical Care Medicine, People's Liberation Army General Hospital, Beijing, China.
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  • For correspondence: [email protected] [email protected]
Stephan Ehrmann
CHRU Tours, Médecine Intensive Réanimation, CIC Institut National de la Santé et de la Recherche Médicale 1415, CRICS-TriggerSEP F-CRIN Research Network, Tours, France.
Institut National de la Santé et de la Recherche Médicale, Centre d’étude des pathologies respiratoires, U1100, Université de Tours, Tours, France.
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    Fig. 1.

    Global distribution of the 1,358 participants. Among these 1,358 participants, the majority were from mainland China (27%); Taiwan (8%); United States (25%); and Europe (30%), including France, United Kingdom, Spain and others.

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    Fig. 2.

    High-flow nasal cannula (HFNC) indications. Overall (red bar), postextubation hypoxemia was the top HFNC indication, followed by moderate hypoxemia, mild hypoxemia and postextubation COPD. In North America, more clinicians preferred to use HFNC to treat severe hypoxemia than other areas; whereas, in China, more clinicians used HFNC to facilitate extubation for patients with COPD, and more European clinicians used HFNC to improve or maintain peri-intubation oxygenation.

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    Fig. 3.

    Aerosol therapy during high-flow nasal cannula (HFNC) treatment. When patients required short-term aerosol treatment during HFNC therapy, 33% of the participants (331/1,014) discontinued HFNC treatment to use a conventional aerosol device, 40% (403/1,014) placed the nebulizer with a mask over the nasal cannula, and 24% (248/1,014) placed the nebulizer in-line within the HFNC circuit. Of the 248 participants who delivered aerosol via HFNC, 40% used a vibrating mesh nebulizer, 30% used an ultrasonic nebulizer, and 28% used a small-volume jet nebulizer.

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Respiratory Care: 66 (9)
Respiratory Care
Vol. 66, Issue 9
1 Sep 2021
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Worldwide Clinical Practice of High-Flow Nasal Cannula and Concomitant Aerosol Therapy in the Adult ICU Setting
Jie Li, Meilien Tu, Lei Yang, Guoqiang Jing, James B Fink, Chris Burtin, Armèle Dornelas de Andrade, Lingyue Gong, Lixin Xie, Stephan Ehrmann
Respiratory Care Sep 2021, 66 (9) 1416-1424; DOI: 10.4187/respcare.08996

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Worldwide Clinical Practice of High-Flow Nasal Cannula and Concomitant Aerosol Therapy in the Adult ICU Setting
Jie Li, Meilien Tu, Lei Yang, Guoqiang Jing, James B Fink, Chris Burtin, Armèle Dornelas de Andrade, Lingyue Gong, Lixin Xie, Stephan Ehrmann
Respiratory Care Sep 2021, 66 (9) 1416-1424; DOI: 10.4187/respcare.08996
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Keywords

  • high-flow nasal cannula
  • aerosol therapy
  • survey
  • Hypoxemia
  • transnasal pulmonary aerosol delivery

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