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Research ArticleOriginal Research

Clinical Implications of Bronchodilator Testing: Diagnosing and Differentiating COPD and Asthma-COPD Overlap

Srinadh Annangi and Angel O Coz-Yataco
Respiratory Care April 2022, 67 (4) 440-447; DOI: https://doi.org/10.4187/respcare.09215
Srinadh Annangi
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Kentucky College of Medicine, Lexington, Kentucky; and Division of Pulmonary and Critical Care Medicine, Harrison Memorial Hospital, Cynthiana, Kentucky.
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  • For correspondence: [email protected]
Angel O Coz-Yataco
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Kentucky College of Medicine, Lexington, Kentucky; and Division of Pulmonary and Critical Care Medicine, Harrison Memorial Hospital, Cynthiana, Kentucky.
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References

  1. 1.↵
    1. Croft JB,
    2. Wheaton AG,
    3. Liu Y,
    4. Xu F,
    5. Lu H,
    6. Matthews KA,
    7. et al
    . Urban-rural county and state differences in chronic obstructive pulmonary disease—United States, 2015. Mmwr Morb Mortal Wkly Rep 2018;67(7):205-211.
    OpenUrlPubMed
  2. 2.↵
    1. Kochanek K,
    2. Murphy S,
    3. Xu J,
    4. Arias E
    . Mortality in the United States, 2016. NCHS Data Brief, no 293. National Center for Health Statistics 2017.
  3. 3.↵
    1. Ford ES,
    2. Murphy LB,
    3. Khavjou O,
    4. Giles WH,
    5. Holt JB,
    6. Croft JB
    . Total and state-specific medical and absenteeism costs of COPD among adults aged 18 years in the United States for 2010 and projections through 2020. Chest 2015;147(1):31-45.
    OpenUrlCrossRefPubMed
  4. 4.↵
    1. Celli BR,
    2. MacNee W,
    3. Agusti A,
    4. Anzueto A,
    5. Berg B,
    6. Buist AS,
    7. et al
    ; ATS/ERS Task Force. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 2004;23(6):932-946.
    OpenUrlFREE Full Text
  5. 5.↵
    Global Initiative for Chronic Obstructive Lung Disease (GOLD) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: 2019 update. Available at: https://goldcopd.org. Accessed March 1, 2019.
  6. 6.↵
    1. Fortis S,
    2. Eberlein M,
    3. Georgopoulos D,
    4. Comellas AP
    . Predictive value of prebronchodilator and post–bronchodilator spirometry for COPD features and outcomes. BMJ Open Respir Res 2017;4(1):e000213.
    OpenUrlAbstract/FREE Full Text
  7. 7.↵
    1. Arne M,
    2. Lisspers K,
    3. Ställberg B,
    4. Boman G,
    5. Hedenström H,
    6. Janson C,
    7. et al
    . How often is diagnosis of COPD confirmed with spirometry? Respiratory Medicine 2010;104(4):550-556.
    OpenUrlCrossRefPubMed
  8. 8.
    1. De Marco R,
    2. Accordini S,
    3. Cerveri I,
    4. Corsico A,
    5. Sunyer J,
    6. Neukirch F,
    7. et al
    . An international survey of chronic obstructive pulmonary disease in young adults according to GOLD stages. Thorax 2004;59(2):120-125.
    OpenUrlAbstract/FREE Full Text
  9. 9.
    1. Miravitlles M,
    2. de la Roza C,
    3. Naberan K,
    4. Lamban M,
    5. Gobartt E,
    6. Martin A
    . Use of spirometry and patterns of prescribing in COPD in primary care. Respir Med 2007;101(8):1753-1760.
    OpenUrlCrossRefPubMedWeb of Science
  10. 10.
    1. Gershon AS,
    2. Hwee J,
    3. Croxford R,
    4. Aaron SD,
    5. To T
    . Patient and physician factors associated with pulmonary function testing for COPD: a population study. Chest 2014;145(2):272-281.
    OpenUrlCrossRefPubMedWeb of Science
  11. 11.
    1. Collins BF,
    2. Feemster LC,
    3. Rinne ST,
    4. Au DH
    . Factors predictive of airflow obstruction among veterans with presumed empirical diagnosis and treatment of COPD. Chest 2015;147(2):369-376.
    OpenUrlCrossRefPubMed
  12. 12.
    1. Lee TA,
    2. Bartle B,
    3. Weiss KB
    . Spirometry use in clinical practice following diagnosis of COPD. Chest 2006;129(6):1509-1515.
    OpenUrlCrossRefPubMedWeb of Science
  13. 13.↵
    1. Han MK,
    2. Kim MG,
    3. Mardon R,
    4. Renner P,
    5. Sullivan S,
    6. Diette GB,
    7. et al
    . Spirometry utilization for COPD: how do we measure up? Chest 2007;132(2):403-409.
    OpenUrlCrossRefPubMed
  14. 14.
    1. Sterk P
    . Let's not forget: the GOLD criteria for COPD are based on post-bronchodilator FEV1
  15. 15.↵
    1. Heffler E,
    2. Crimi C,
    3. Mancuso S,
    4. Campisi R,
    5. Puggioni F,
    6. Brussino L,
    7. et al
    . Misdiagnosis of asthma and COPD and underuse of spirometry in primary care unselected patients. Respir Med 2018;142:48-52.
    OpenUrlCrossRefPubMed
  16. 16.↵
    1. Pérez-Padilla R,
    2. Hallal PC,
    3. Vázquez-García JC,
    4. Muiño A,
    5. Máquez M,
    6. López MV,
    7. et al
    . Impact of bronchodilator use on the prevalence of COPD in population-based samples. COPD: Journal of Chronic Obstructive Pulmonary Disease 2007;4(2):113-120.
    OpenUrl
  17. 17.↵
    1. Johannessen A,
    2. Omenaas ER,
    3. Bakke PS,
    4. Gulsvik A
    . Implications of reversibility testing on prevalence and risk factors for chronic obstructive pulmonary disease: a community study. Thorax 2005;60(10):842-847.
    OpenUrlAbstract/FREE Full Text
  18. 18.↵
    1. Maselli DJ,
    2. Hardin M,
    3. Christenson SA,
    4. Hanania NA,
    5. Hersh CP,
    6. Adams SG,
    7. et al
    . Clinical approach to the therapy of asthma-COPD overlap. Chest 2019;155(1):168-177.
    OpenUrlCrossRef
  19. 19.↵
    1. Sin DD,
    2. Miravitlles M,
    3. Mannino DM,
    4. Soriano JB,
    5. Price D,
    6. Celli BR,
    7. et al
    . What is asthma−COPD overlap syndrome? Toward a consensus definition from a round table discussion. Eur Respir J 2016;48(3):664-673.
    OpenUrlAbstract/FREE Full Text
  20. 20.↵
    1. Soler-Cataluna JJ,
    2. Cosío B,
    3. Izquierdo JL,
    4. López-Campos JL,
    5. Marín JM,
    6. Agüero R,
    7. et al
    . Consensus document on the overlap phenotype COPD–asthma in COPD. Archivos de Bronconeumología (English Edition) 2012;48(9):331-337.
    OpenUrl
  21. 21.↵
    Centers for Disease Control and Prevention. National Center for Health Statistics. National Health and Nutrition Examination Survey Data, 2007 to 2012. Hyattsville, Maryland: Available at: https://wwwn.cdc.gov/nchs/nhanes/default.aspx. Accessed January 2019.
  22. 22.↵
    Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey (NHANES), Respiratory Health Bronchodilator Procedures Manual. https://www.cdc.gov/nchs/data/nhanes/nhanes_07_08/Bronchodilator.pdf
  23. 23.↵
    Centers for Disease Control and Prevention (CDC). National Health and Nutrition Examination Survey (NHANES). Respiratory Health Spirometry Procedures Manual. https://www.cdc.gov/nchs/data/nhanes/nhanes_07_08/spirometry.pdf
  24. 24.↵
    1. Miller MR,
    2. Hankinson J,
    3. Brusasco V,
    4. Burgos F,
    5. Casaburi R,
    6. Coates A,
    7. et al
    ; ATS/ERS Task Force. ATS/ERS task force: standardization of spirometry. Eur Respir J 2005;26(2):319-338.
    OpenUrlAbstract/FREE Full Text
  25. 25.↵
    Centers for Disease Control and Prevention. NHANES Laboratory/Medical Technologists Procedures, 2001.
  26. 26.↵
    1. Kamijo A,
    2. Soma T,
    3. Uchida Y,
    4. Araki R,
    5. Kobayashi T,
    6. Inoue H,
    7. et al
    . Prevalence of allergic rhinitis among asthmatic patients in two different seasons. Arerugi 2013;62(12):1642-1650.
    OpenUrl
  27. 27.
    1. Bugiani M,
    2. Carosso A,
    3. Migliore E,
    4. Piccioni P,
    5. Corsico A,
    6. Olivieri M,
    7. et al
    ; ISAYA (ECRHS Italy) Study Group. Allergic rhinitis and asthma comorbidity in a survey of young adults in Italy. Allergy 2005;60(2):165-170.
    OpenUrlCrossRefPubMedWeb of Science
  28. 28.↵
    1. Navarro A,
    2. Valero A,
    3. Juliá B,
    4. Quirce S
    . Coexistence of asthma and allergic rhinitis in adult patients attending allergy clinics: ONEAIR study. J Investig Allergol Clin Immunol 2008;18(4):233-238.
    OpenUrlPubMed
  29. 29.↵
    1. Cosio BG,
    2. Soriano JB,
    3. López-Campos JL,
    4. Calle-Rubio M,
    5. Soler-Cataluna JJ,
    6. de-Torres JP,
    7. et al
    . Defining the asthma-COPD overlap syndrome in a COPD cohort. Chest 2016;149(1):45-52.
    OpenUrlCrossRefPubMed
  30. 30.↵
    1. Miravitlles M,
    2. Soler-Cataluna JJ,
    3. Calle M,
    4. Soriano JB
    . Treatment of COPD by clinical phenotypes: putting old evidence into clinical practice. Eur Respir J 2013;41(6):1252-1256.
    OpenUrlAbstract/FREE Full Text
  31. 31.
    1. Weatherall M,
    2. Travers J,
    3. Shirtcliffe PM,
    4. Marsh SE,
    5. Williams MV,
    6. Nowitz MR,
    7. et al
    . Distinct clinical phenotypes of airways disease defined by cluster analysis. Eur Respir J 2009;34(4):812-818.
    OpenUrlAbstract/FREE Full Text
  32. 32.
    1. Gibson PG,
    2. Simpson JL
    . The overlap syndrome of asthma and COPD: what are its features and how important is it? Thorax 2009;64(8):728-735.
    OpenUrlAbstract/FREE Full Text
  33. 33.
    1. Postma DS,
    2. Rabe KF
    . The asthma-COPD overlap syndrome. N Engl J Med 2015;373(13):1241-1249.
    OpenUrlCrossRefPubMed
  34. 34.↵
    1. Leung JM,
    2. Sin DD
    . Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets. BMJ 2017;358:j3772.
    OpenUrlAbstract/FREE Full Text
  35. 35.↵
    1. Martinez F,
    2. Criner G,
    3. Hoffman E,
    4. Wise R,
    5. Flaherty K,
    6. Make B
    . Spirometric bronchoreversibility (SBR) in emphysema patients. Proc Am Thorac Soc 2005;1.
  36. 36.↵
    1. Anthonisen N,
    2. Lindgren P,
    3. Tashkin D,
    4. Kanner R,
    5. Scanlon P,
    6. Connett J
    ; Lung Health Study Research Group. Bronchodilator response in the lung health study over 11 years. Eur Respir J 2005;26(1):45-51.
    OpenUrlAbstract/FREE Full Text
  37. 37.↵
    1. Kauppi P,
    2. Kupiainen H,
    3. Lindqvist A,
    4. Tammilehto L,
    5. Kilpelainen M,
    6. Kinnula VL,
    7. et al
    . Overlap syndrome of asthma and COPD predicts low quality of life. J Asthma 2011;48(3):279-285.
    OpenUrlCrossRefPubMedWeb of Science
  38. 38.
    1. Hardin M,
    2. Silverman EK,
    3. Barr RG,
    4. Hansel NN,
    5. Schroeder JD,
    6. Make BJ,
    7. et al
    ; the COPDGene Investigators. The clinical features of the overlap between COPD and asthma. Respir Res 2011;12(1):1.
    OpenUrlCrossRefPubMed
  39. 39.
    1. Miravitlles M,
    2. Soriano JB,
    3. Ancochea J,
    4. Muñoz L,
    5. Duran-Tauleria E,
    6. Sánchez G,
    7. et al
    . Characterization of the overlap COPD-asthma phenotype. Focus on physical activity and health status. Respiratory Medicine 2013;107(7):1053-1060.
    OpenUrlCrossRefPubMed
  40. 40.
    1. Shaya FT,
    2. Dongyi D,
    3. Akazawa MO,
    4. Blanchette CM,
    5. Wang J,
    6. Mapel DW,
    7. et al
    . Burden of concomitant asthma and COPD in a Medicaid population. Chest 2008;134(1):14-19.
    OpenUrlCrossRefPubMedWeb of Science
  41. 41.
    1. Rhee CK,
    2. Yoon HK,
    3. Yoo KH,
    4. Kim YS,
    5. Lee SW,
    6. Park YB,
    7. et al
    . Medical utilization and cost in patients with overlap syndrome of chronic obstructive pulmonary disease and asthma. COPD: Journal of Chronic Obstructive Pulmonary Disease 2014;11(2):163-170.
    OpenUrl
  42. 42.
    1. Menezes AMB,
    2. de Oca MM,
    3. Pérez-Padilla R,
    4. Nadeau G,
    5. Wehrmeister FC,
    6. Lopez-Varela MV,
    7. et al
    . Increased risk of exacerbation and hospitalization in subjects with an overlap phenotype: COPD-asthma. Chest 2014;145(2):297-304.
    OpenUrlCrossRefPubMedWeb of Science
  43. 43.
    1. Diaz-Guzman E,
    2. Khosravi M,
    3. Mannino DM
    . Asthma, chronic obstructive pulmonary disease, and mortality in the US population. COPD: Journal of Chronic Obstructive Pulmonary Disease 2011;8(6):400-407.
    OpenUrl
  44. 44.↵
    1. Alshabanat A,
    2. Zafari Z,
    3. Albanyan O,
    4. Dairi M,
    5. FitzGerald J
    . Asthma and COPD overlap syndrome (ACOS): a systematic review and meta-analysis. PloS One 2015;10(9):e0136065.
    OpenUrlCrossRefPubMed
  45. 45.↵
    1. Lee S-Y,
    2. Park HY,
    3. Kim EK,
    4. Lim SY,
    5. Rhee CK,
    6. Hwang YI,
    7. et al
    . Combination therapy of inhaled steroids and long-acting beta2-agonists in asthma–COPD overlap syndrome. Int J Chron Obstruct Pulmon Dis 2016;11:2797-2803.
    OpenUrlPubMed
  46. 46.↵
    GOLD. Diagnosis of Diseases of Chronic Airflow Limitation: Asthma, COPD and Asthma-COPD Overlap Syndrome (ACOS).
  47. 47.↵
    1. Sá-Sousa A,
    2. Jacinto T,
    3. Azevedo LF,
    4. Morais-Almeida M,
    5. Robalo-Cordeiro C,
    6. Bugalho-Almeida A,
    7. et al
    . Operational definitions of asthma in recent epidemiological studies are inconsistent. Clin Transl Allergy 2014;4(1):24.
    OpenUrlPubMed
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Respiratory Care: 67 (4)
Respiratory Care
Vol. 67, Issue 4
1 Apr 2022
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Clinical Implications of Bronchodilator Testing: Diagnosing and Differentiating COPD and Asthma-COPD Overlap
Srinadh Annangi, Angel O Coz-Yataco
Respiratory Care Apr 2022, 67 (4) 440-447; DOI: 10.4187/respcare.09215

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Clinical Implications of Bronchodilator Testing: Diagnosing and Differentiating COPD and Asthma-COPD Overlap
Srinadh Annangi, Angel O Coz-Yataco
Respiratory Care Apr 2022, 67 (4) 440-447; DOI: 10.4187/respcare.09215
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