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Abstract
COPD remains one of the leading causes of death worldwide. The impact of smoking and air pollution remain important causative factors. Traditional classification of COPD includes the overlap of emphysema, chronic bronchitis and asthma. More recently the COPDGene definition includes the terms possible, probable and definite COPD. These are supported by findings from exposures, symptoms, spirometry and radiologic imaging. This new approach can lead to earlier diagnosis and modification of risk factors, earlier therapeutic intervention and improved treatments of established disease.
Footnotes
- Correspondence: David M Mannino MD, Department of Medicine, University of Kentucky College of Medicine, 800 Rose Street, Lexington, KY 40536. E-mail: dmannino{at}uky.edu
Dr Mannino discloses relationships with GlaxoSmithKline and the COPD Foundation.
Dr Mannino presented a version of this article as the Thomas L Petty Memorial Lecture at AARC Congress 2021 LIVE!, held virtually December 3, 2021.
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