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Dear Editor,
We would like to thank Dr Bruitman-Kruizinga and Dr Schultz for their interest in our study1 and their important comments. The authors postulate that measuring mechanical power from continuous recordings in our study yielded a higher mechanical power when compared to previous studies, and they propose using the more widely applied simplified formula:2 We would like to emphasize that this mathematical approximation has only been validated during volume controlled mechanical ventilation,3,4 and some authors have suggested alternative formulas.3⇓⇓-6 Most importantly, the above formula has not been validated in patients receiving adaptive support ventilation (ASV) or other pressure-regulated modes of ventilation such as adaptive pressure ventilation (APV) (which were the 2 ventilator modes utilized in the initial study). In response to the comments by Dr Bruitman-Kruizinga and Dr Schultz, we calculated mechanical power using this formula, which was 21.8 [interquartile range [IQR] 18.9–31.8] J/min in ASV and 22.3 [IQR 19.2–29.8] J/min in …
Correspondence: Elias Baedorf-Kassis MD. E-mail: Enbaedor{at}bidmc.harvard.edu
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