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Research ArticleSymposium: Research and Publication in Respiratory Care

How to Conduct a Systematic Review and Meta-Analysis: A Guide for Clinicians

Marco Zaccagnini and Jie Li
Respiratory Care September 2023, 68 (9) 1295-1308; DOI: https://doi.org/10.4187/respcare.10971
Marco Zaccagnini
School of Physical and Occupational Therapy, McGill University, Montréal, Québec, Canada; and Department of Respiratory Therapy, McGill University Health Centre, Montréal, Québec, Canada.
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Jie Li
Department Cardiopulmonary Sciences, Division of Respiratory Care, Rush University, Chicago, Illinois.
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  • For correspondence: [email protected]
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Abstract

Evidence-based practice relies on using research evidence to guide clinical decision-making. However, staying current with all published research can be challenging. Many clinicians use review articles that apply predefined methods to locate, identify, and summarize all available evidence on a topic to guide clinical decision-making. This paper discusses the role of review articles, including narrative, scoping, and systematic reviews, to synthesize existing evidence and generate new knowledge. It provides a step-by-step guide to conducting a systematic review and meta-analysis, covering key steps such as formulating a research question, selecting studies, evaluating evidence quality, and reporting results. This paper is intended as a resource for clinicians looking to learn how to conduct systematic reviews and advance evidence-based practice in the field.

  • systematic review
  • review
  • meta-analysis
  • scoping review
  • narrative review
  • knowledge synthesis

Footnotes

  • Correspondence: Jie Li PhD RRT RRT-ACCS RRT-NPS FAARC, 600 S Paulina St Suite 765, Chicago, IL 60612. E-mail: Jie_Li{at}rush.edu
  • Dr Li discloses relationships with Fisher & Paykel Healthcare, Aerogen, the Rice Foundation, the American Association for Respiratory Care, and Heyer. Dr Li is a section editor for Respiratory Care. Mr Zaccagnini is an editorial board member for Respiratory Care and discloses funding from the Fonds de Recherche du Québec - Santé.

  • Dr Li presented a version of this paper at AARC Congress 2022, held November 9–12, 2022, in New Orleans, Louisiana.

  • Supplementary material related to this paper is available at http://www.rcjournal.com.

  • Copyright © 2023 by Daedalus Enterprises
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Respiratory Care: 68 (9)
Respiratory Care
Vol. 68, Issue 9
1 Sep 2023
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How to Conduct a Systematic Review and Meta-Analysis: A Guide for Clinicians
Marco Zaccagnini, Jie Li
Respiratory Care Sep 2023, 68 (9) 1295-1308; DOI: 10.4187/respcare.10971

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How to Conduct a Systematic Review and Meta-Analysis: A Guide for Clinicians
Marco Zaccagnini, Jie Li
Respiratory Care Sep 2023, 68 (9) 1295-1308; DOI: 10.4187/respcare.10971
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  • Article
    • Abstract
    • Introduction
    • Types of Reviews
    • How to Conduct a Systematic Review
    • Meta-Analysis
    • Presenting Systematic Review (and Meta-Analysis) Results
    • The Discussion of a Systematic Review (and Meta-Analysis)
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Keywords

  • systematic review
  • review
  • meta-analysis
  • scoping review
  • narrative review
  • knowledge synthesis

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