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Research ArticleOriginal Research

Systemic Determinants of Exercise Intolerance in Patients With Fibrotic Interstitial Lung Disease and Severely Impaired DLCO

Reginald M Smyth, Matthew D James, Sandra G Vincent, Kathryn M Milne, Mathieu Marillier, Nicolle J Domnik, Christopher M Parker, Juan P de-Torres, Onofre Moran-Mendoza, Devin B Phillips, Denis E O’Donnell and J Alberto Neder
Respiratory Care August 2023, respcare.11147; DOI: https://doi.org/10.4187/respcare.11147
Reginald M Smyth
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada.
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Matthew D James
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada.
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Sandra G Vincent
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada.
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Kathryn M Milne
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada; and Centre for Heart Lung Innovation, Providence Health Care Research Institute, University of British Columbia, St. Paul’s Hospital, Vancouver, British Columbia, Canada.
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Mathieu Marillier
HP2 Laboratory, INSERM U1300, Grenoble Alpes University, Grenoble, France.
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Nicolle J Domnik
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada; and Department of Biomedical and Molecular Sciences and Department of Medicine, Queen’s University, Kingston, Ontario, Canada.
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Christopher M Parker
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada.
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Juan P de-Torres
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada; and Pulmonary Department, Clínica Universidad de Navarra and Instituto de Investigación Sanitaria de Navarra, Navarra, Spain.
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Onofre Moran-Mendoza
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada.
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Devin B Phillips
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada; and School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada.
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Denis E O’Donnell
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada.
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J Alberto Neder
Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada.
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  • For correspondence: [email protected]
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In this issue

Respiratory Care: 68 (12)
Respiratory Care
Vol. 68, Issue 12
1 Dec 2023
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Systemic Determinants of Exercise Intolerance in Patients With Fibrotic Interstitial Lung Disease and Severely Impaired DLCO
Reginald M Smyth, Matthew D James, Sandra G Vincent, Kathryn M Milne, Mathieu Marillier, Nicolle J Domnik, Christopher M Parker, Juan P de-Torres, Onofre Moran-Mendoza, Devin B Phillips, Denis E O’Donnell, J Alberto Neder
Respiratory Care Aug 2023, respcare.11147; DOI: 10.4187/respcare.11147

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Systemic Determinants of Exercise Intolerance in Patients With Fibrotic Interstitial Lung Disease and Severely Impaired DLCO
Reginald M Smyth, Matthew D James, Sandra G Vincent, Kathryn M Milne, Mathieu Marillier, Nicolle J Domnik, Christopher M Parker, Juan P de-Torres, Onofre Moran-Mendoza, Devin B Phillips, Denis E O’Donnell, J Alberto Neder
Respiratory Care Aug 2023, respcare.11147; DOI: 10.4187/respcare.11147
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Keywords

  • dyspnea
  • exercise testing
  • interstitial lung disease
  • gas exchange
  • lung mechanics

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