RT Journal Article SR Electronic T1 The Integrative Weaning Index in Elderly ICU Subjects JF Respiratory Care FD American Association for Respiratory Care SP 333 OP 339 DO 10.4187/respcare.04524 VO 62 IS 3 A1 Azeredo, Leandro M A1 Nemer, Sérgio N A1 Barbas, Carmen SV A1 Caldeira, Jefferson B A1 Noé, Rosângela A1 Guimarães, Bruno L A1 Caldas, Célia P YR 2017 UL http://rc.rcjournal.com/content/62/3/333.abstract AB BACKGROUND: With increasing life expectancy and ICU admission of elderly patients, mechanical ventilation, and weaning trials have increased worldwide.METHODS: We evaluated a cohort with 479 subjects in the ICU. Patients younger than 18 y, tracheostomized, or with neurologic diseases were excluded, resulting in 331 subjects. Subjects ≥70 y old were considered elderly, whereas those <70 y old were considered non-elderly. Besides the conventional weaning indexes, we evaluated the performance of the integrative weaning index (IWI). The probability of successful weaning was investigated using relative risk and logistic regression. The Hosmer-Lemeshow goodness-of-fit test was used to calibrate and the C statistic was calculated to evaluate the association between predicted probabilities and observed proportions in the logistic regression model.RESULTS: Prevalence of successful weaning in the sample was 83.7%. There was no difference in mortality between elderly and non-elderly subjects (P = .16), in days of mechanical ventilation (P = .22) and days of weaning (P = .55). In elderly subjects, the IWI was the only respiratory variable associated with mechanical ventilation weaning in this population (P < .001).CONCLUSIONS: The IWI was the independent variable found in weaning of elderly subjects that may contribute to the critical moment of this population in intensive care.