TY - JOUR T1 - Immediate Changes in Blood-Gas Tensions During Chest Physiotherapy With Positive Expiratory Pressure and Oscillating Positive Expiratory Pressure in Patients With Cystic Fibrosis JF - Respiratory Care SP - 1154 LP - 1161 VL - 51 IS - 10 AU - Anna-Lena B Lagerkvist AU - Gunilla M Sten AU - Staffan B Redfors AU - Anders G Lindblad AU - Ola Hjalmarson Y1 - 2006/10/01 UR - http://rc.rcjournal.com/content/51/10/1154.abstract N2 - OBJECTIVE: To assess and compare immediate effects of chest physiotherapy with positive expiratory pressure (PEP) versus oscillating PEP on transcutaneously measured blood-gas tensions in patients with cystic fibrosis. METHODS: Fifteen patients (mean age 12.5 y, range 6.9–21.5 y) participated. The treatments were randomized and performed on 2 separate occasions, 8 weeks apart. Spirometry was conducted before and after each treatment. We transcutaneously measured oxygen tension (PtO2) and carbon dioxide tension (PtCO2) 20 min before, during, and 10 min after each treatment. RESULTS: There were no changes in spirometry values. During PEP, different trends in blood-gas tension were seen, and there were no consistent changes. During oscillating PEP, PtO2 increased and PtCO2 decreased. During oscillating PEP, PtCO2 was lower and the intra-individual change in PtCO2 was more pronounced than during PEP. The results obtained immediately after oscillating PEP showed a higher PtO2 and a lower PtCO2 than with PEP. CONCLUSION: PEP and oscillating PEP can both cause transitory effects on blood gases in patients with cystic fibrosis. However, oscillating PEP alters blood-gas tensions more than does PEP, and hyperventilation during oscillating PEP may reduce treatment time. ER -