RT Journal Article
SR Electronic
T1 Mortality of Adult Critically Ill Subjects With Cancer
JF Respiratory Care
FD American Association for Respiratory Care
SP 615
OP 622
DO 10.4187/respcare.05210
VO 62
IS 5
A1 Regis Goulart Rosa
A1 Tulio Frederico Tonietto
A1 Bruno Achutti Duso
A1 Juçara Gasparetto Maccari
A1 Roselaine Pinheiro de Oliveira
A1 William Rutzen
A1 Laura Madeira
A1 Aline Ascoli
A1 Rachel Hessler
A1 Paola Morandi
A1 Ricardo Viegas Cremonese
A1 Felippe Leopoldo Dexheimer Neto
A1 Luciana Tagliari
A1 Patrícia de Campos Balzano
A1 José Hervê Diel Barth
A1 Cassiano Teixeira
YR 2017
UL http://rc.rcjournal.com/content/62/5/615.abstract
AB BACKGROUND: Cancer patients may require intensive care support for postoperative care, complications associated with underlying malignancy, or toxicities related to cancer therapy. The higher mortality rates found in this population than in the population of ICU patients without cancer may be attributable to confounding due to a higher prevalence of multiple organic dysfunctions at ICU admission in patients with malignancy; however, data regarding this hypothesis are scarce. Accordingly, we performed the present study to compare the crude and propensity score-matched mortality rates between adult subjects with and without cancer admitted to a mixed medical-surgical ICU.METHODS: We conducted a retrospective analysis of a comprehensive longitudinal ICU database in a tertiary referral hospital in Southern Brazil. All adult subjects who were admitted to the ICU from January 2008 to December 2014 were evaluated. Crude and propensity score-matched all-cause 30-d mortality rates of critically ill subjects with cancer were compared with those of critically ill subjects without cancer.RESULTS: A total of 4,221 subjects were evaluated. The survival analysis revealed that the crude mortality rate was higher among subjects with cancer than among subjects without cancer (18.7% vs 10.2%, P < .001). However, after matching by propensity score, the 30-d mortality rates of subjects with and without cancer were similar (18.5% vs 15.2%, P = .17).CONCLUSIONS: The present study failed to show an association between malignancy and all-cause 30-d mortality rate in adult subjects admitted to a mixed medical-surgical ICU. The propensity score-matched analysis showed no evidence of excessive mortality due to cancer diagnosis.