RT Journal Article
SR Electronic
T1 Bronchial Mucus Transport
JF Respiratory Care
FD American Association for Respiratory Care
SP 1150
OP 1158
VO 52
IS 9
A1 Cees P van der Schans
YR 2007
UL http://rc.rcjournal.com/content/52/9/1150.abstract
AB Effective clearance of inhaled particles requires mucus production and continuous mucus transport from the lower airways to the oropharynx. Mucus production takes place mainly in the peripheral airways. Mucus transport is achieved by the action of the ciliated cells that cover the inner surface of the airways (mucociliary transport) and by expiratory airflow. The capacity for mucociliary transport is highest in the peripheral airways, whereas the capacity for airflow transport is highest in the central airways. In patients with airways disease, mucociliary transport may be impaired and airflow transport may become the most important mucus transport mechanism.