RT Journal Article SR Electronic T1 Noninvasive Ventilation As an Alternative to Endotracheal Intubation During Tracheotomy in Advanced Neuromuscular Disease JF Respiratory Care FD American Association for Respiratory Care SP 1728 OP 1733 VO 52 IS 12 A1 David Orlikowski A1 Hélène Prigent A1 Jésus Gonzalez-Bermejo A1 Philippe Aubert A1 Frédéric Lofaso A1 Jean Claude Raphael A1 Bernard Clair YR 2007 UL http://rc.rcjournal.com/content/52/12/1728.abstract AB OBJECTIVE: To compare conventional tracheotomy with endotracheal intubation to tracheotomy with noninvasive positive-pressure ventilation (NPPV) in advanced neuromuscular disease. METHODS: This was a retrospective study of a historical cohort of patients tracheotomized while sedated and intubated versus patients tracheotomized under NPPV and local anesthesia. We recorded previous intubation difficulties, complications (eg, aspiration pneumonia), and hospital stay. RESULTS: Conventional tracheotomy was performed in 7 patients. We performed tracheotomy during NPPV with local anesthesia in 13 patients. All but 3 patients had risk factors for difficult intubation. Hospital stay was 23.3 ± 10.3 d in the conventional group and 25.3 ± 12.9 d in the NPPV group (p = 0.87). The number of pneumonias was higher in the conventional-tracheotomy group (4 vs 1, p = 0.03). CONCLUSION: In neuromuscular patients, performing tracheotomy with NPPV and local anesthesia may help avoid endotracheal intubation and reduce morbidity.