PT - JOURNAL ARTICLE AU - Richard D Branson TI - Patient-Ventilator Interaction: The Last 40 Years AID - 10.4187/respcare.00937 DP - 2011 Jan 01 TA - Respiratory Care PG - 15--24 VI - 56 IP - 1 4099 - http://rc.rcjournal.com/content/56/1/15.short 4100 - http://rc.rcjournal.com/content/56/1/15.full AB - Patient-ventilator synchrony is a complex issue affected by ventilator performance, patient characteristics, and the patient-ventilator interface. The history of patient-ventilator interaction includes avoidance of pharmacalogic paralysis, the development of spontaneous breathing systems, microprocessor technology to maximize interaction, and closed-loop control. While most clinicians agree that patient-ventilator synchrony is desirable, there remain no cause-and-effect data that asynchrony is associated with poor outcome.