TY - JOUR T1 - Patient-Ventilator Interaction: The Last 40 Years JF - Respiratory Care SP - 15 LP - 24 DO - 10.4187/respcare.00937 VL - 56 IS - 1 AU - Richard D Branson Y1 - 2011/01/01 UR - http://rc.rcjournal.com/content/56/1/15.abstract N2 - Patient-ventilator synchrony is a complex issue affected by ventilator performance, patient characteristics, and the patient-ventilator interface. The history of patient-ventilator interaction includes avoidance of pharmacalogic paralysis, the development of spontaneous breathing systems, microprocessor technology to maximize interaction, and closed-loop control. While most clinicians agree that patient-ventilator synchrony is desirable, there remain no cause-and-effect data that asynchrony is associated with poor outcome. ER -