RT Journal Article SR Electronic T1 Patient-Ventilator Interaction: The Last 40 Years JF Respiratory Care FD American Association for Respiratory Care SP 15 OP 24 DO 10.4187/respcare.00937 VO 56 IS 1 A1 Richard D Branson YR 2011 UL http://rc.rcjournal.com/content/56/1/15.abstract AB Patient-ventilator synchrony is a complex issue affected by ventilator performance, patient characteristics, and the patient-ventilator interface. The history of patient-ventilator interaction includes avoidance of pharmacalogic paralysis, the development of spontaneous breathing systems, microprocessor technology to maximize interaction, and closed-loop control. While most clinicians agree that patient-ventilator synchrony is desirable, there remain no cause-and-effect data that asynchrony is associated with poor outcome.