RT Journal Article SR Electronic T1 Inhaled Medical Gases: More to Breathe Than Oxygen JF Respiratory Care FD American Association for Respiratory Care SP 1341 OP 1359 DO 10.4187/respcare.01442 VO 56 IS 9 A1 Michael A Gentile YR 2011 UL http://rc.rcjournal.com/content/56/9/1341.abstract AB The mixture of oxygen and nitrogen is usually sufficient to achieve the therapeutic objective of supporting adequate gas exchange. Pediatric and neonatal patients have an assortment of physiologic conditions that may require adjunctive inhaled gases to treat the wide variety of diseases seen in this heterogeneous population. Inhaled nitric oxide, helium oxygen mixtures, inhaled anesthetics, hypercarbic mixtures, hypoxic mixtures, inhaled carbon monoxide, and hydrogen sulfide have been used to alter physiology in an attempt to improve patient outcomes. Balancing the therapeutic potential, possible adverse effects, and the complexity of the technical aspects of gas delivery, it is essential that clinicians thoroughly understand the application of medical gas therapy beyond the traditional nitrogen/oxygen mixture.