RT Journal Article SR Electronic T1 High-Frequency Chest-Wall Oscillation in a Noninvasive-Ventilation-Dependent Patient With Type 1 Spinal Muscular Atrophy JF Respiratory Care FD American Association for Respiratory Care SP 1840 OP 1843 DO 10.4187/respcare.01155 VO 56 IS 11 A1 Keating, Joanna M A1 Collins, Nicola A1 Bush, Andrew A1 Chatwin, Michelle YR 2011 UL http://rc.rcjournal.com/content/56/11/1840.abstract AB With the recent increased use of noninvasive ventilation, the prognoses of children with neuromuscular disease has improved significantly. However, children with muscle weakness remain at risk for recurrent respiratory infection and atelectasis. We report the case of a young girl with type 1 spinal muscular atrophy who was dependent on noninvasive ventilation, and in whom conventional secretion-clearance physiotherapy became insufficient to clear secretions. We initiated high-frequency chest-wall oscillation (HFCWO) as a rescue therapy, and she had improved self-ventilation time. This is the first case report of HFCWO for secretion clearance in a severely weak child with type 1 spinal muscular atrophy. In a patient with neuromuscular disease and severe respiratory infection and compromise, HFCWO can be used safely in combination with conventional secretion-clearance physiotherapy.