@article {Strickland344, author = {Shawna L Strickland and M Timothy Hogan and Rosemary G Hogan and Harjyot S Sohal and Wayland N McKenzie and Gregory F Petroski}, title = {A Randomized Multi-Arm Repeated-Measures Prospective Study of Several Modalities of Portable Oxygen Delivery During Assessment of Functional Exercise Capacity}, volume = {54}, number = {3}, pages = {344--349}, year = {2009}, publisher = {Respiratory Care}, abstract = {BACKGROUND: Ambulatory oxygen is an important component of long-term oxygen therapy. Pulse-dose technology conserves oxygen and thus increases the operation time of a portable oxygen system. METHODS: We tested 4 ambulatory oxygen systems (Helios, HomeFill, FreeStyle, and the compressed-oxygen cylinder system we regularly provide for long-term oxygen therapy at our Veterans Affairs hospital) with 39 subjects with stage-IV chronic obstructive pulmonary disease. Each subject performed one 6-min walk test with each oxygen system, and we measured blood oxygen saturation (via pulse oximetry [SpO2]), heart rate, and modified Borg dyspnea score, and surveyed the subjects{\textquoteright} preferences about the oxygen systems. We also studied whether the 2 systems that provide gas with a lower oxygen concentration (from a home concentrator or portable concentrator) showed any evidence of not providing adequate oxygenation. RESULTS: With all 4 systems the mean pre-walk SpO2 at the prescribed pulse-dose setting was 95{\textendash}96\%. The mean post-walk SpO2 was 88{\textendash}90\% after each of the 4 walk tests. Between the 4 systems there were no statistically significant differences between the pre-walk-versus-post-walk SpO2 (P = .42). With each system, the pre-walk-versus-post-walk SpO2 difference was between -8\% and -6\%. CONCLUSIONS: Between these 4 ambulatory oxygen systems there were no significant differences in SpO2, walk time, or walk distance, and there was no evidence of inadequate oxygenation with the 2 systems that provide a lower oxygen concentration.}, issn = {0020-1324}, URL = {https://rc.rcjournal.com/content/54/3/344}, eprint = {https://rc.rcjournal.com/content/54/3/344.full.pdf}, journal = {Respiratory Care} }