RT Journal Article SR Electronic T1 A Randomized Multi-Arm Repeated-Measures Prospective Study of Several Modalities of Portable Oxygen Delivery During Assessment of Functional Exercise Capacity JF Respiratory Care FD American Association for Respiratory Care SP 344 OP 349 VO 54 IS 3 A1 Shawna L Strickland A1 M Timothy Hogan A1 Rosemary G Hogan A1 Harjyot S Sohal A1 Wayland N McKenzie A1 Gregory F Petroski YR 2009 UL http://rc.rcjournal.com/content/54/3/344.abstract AB BACKGROUND: Ambulatory oxygen is an important component of long-term oxygen therapy. Pulse-dose technology conserves oxygen and thus increases the operation time of a portable oxygen system. METHODS: We tested 4 ambulatory oxygen systems (Helios, HomeFill, FreeStyle, and the compressed-oxygen cylinder system we regularly provide for long-term oxygen therapy at our Veterans Affairs hospital) with 39 subjects with stage-IV chronic obstructive pulmonary disease. Each subject performed one 6-min walk test with each oxygen system, and we measured blood oxygen saturation (via pulse oximetry [SpO2]), heart rate, and modified Borg dyspnea score, and surveyed the subjects' preferences about the oxygen systems. We also studied whether the 2 systems that provide gas with a lower oxygen concentration (from a home concentrator or portable concentrator) showed any evidence of not providing adequate oxygenation. RESULTS: With all 4 systems the mean pre-walk SpO2 at the prescribed pulse-dose setting was 95–96%. The mean post-walk SpO2 was 88–90% after each of the 4 walk tests. Between the 4 systems there were no statistically significant differences between the pre-walk-versus-post-walk SpO2 (P = .42). With each system, the pre-walk-versus-post-walk SpO2 difference was between −8% and −6%. CONCLUSIONS: Between these 4 ambulatory oxygen systems there were no significant differences in SpO2, walk time, or walk distance, and there was no evidence of inadequate oxygenation with the 2 systems that provide a lower oxygen concentration.